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Evaluation of intraperitoneal lavage cytology before colorectal cancer resection

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International Journal of Colorectal Disease Aims and scope Submit manuscript

Abstract

Purpose

The aim of this study was to assess the usefulness of intraperitoneal lavage cytology (lavage Cy) status before the resection of colorectal cancer as a predictive factor of peritoneal recurrence.

Materials and methods

The lavage Cy-positive [lavage Cy (+)] rate, peritoneal recurrence rate, and 5-year survival rate were examined in 298 cases of colorectal cancer in relation to various clinicopathological factors.

Results

The overall lavage Cy (+) rate was 6.0%. The lavage Cy (+) rate within the group with peritoneal and hepatic metastases was significantly higher than that in the group without metastases (46.7% vs. 3.9% and 26.9% vs. 4.0%, respectively). The lavage Cy (+) rate was not significantly associated with any of the clinicopathological factors examined. The peritoneal recurrence rate was higher in the lavage Cy (+) group than in the lavage Cy-negative [lavage Cy (−)] group, although the difference was not statistically significant. There was no significant difference in survival, regardless of the lavage Cy status, among the 263 patients who underwent curative resection.

Conclusion

The lavage Cy status before resection was not a useful predictive factor of peritoneal recurrence in cases of colorectal cancer.

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Acknowledgments

We thank Dr. Nozawa and technical staff at the pathological unit of Yokohama City University Medical Center, Japan for help with the cytology diagnoses.

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Authors and Affiliations

  1. Department of Surgery, Gastroenterological Center, Yokohama City University, 4-57 Urafunecho, Minami-ku, Yokohama, 232-0024, Japan

    Shoichi Fujii, Mitsuyoshi Ota, Chikara Kunisaki & Hideyuki Ike

  2. Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, 4-9 Hukuura, Kanazawa-ku, Yokohama, 236-0004, Japan

    Hiroshi Shimada, Shigeru Yamagishi & Yasushi Ichikawa

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  1. Shoichi Fujii
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  2. Hiroshi Shimada
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  3. Shigeru Yamagishi
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Correspondence to Shoichi Fujii.

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Fujii, S., Shimada, H., Yamagishi, S. et al. Evaluation of intraperitoneal lavage cytology before colorectal cancer resection. Int J Colorectal Dis 24, 907–914 (2009). https://doi.org/10.1007/s00384-009-0733-z

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  • DOI: https://doi.org/10.1007/s00384-009-0733-z

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