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Inflammatory bowel disease and the lung: is there a link between surgery and bronchiectasis?

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Abstract

Purpose

One-third of patients with inflammatory bowel disease (IBD) has extracolonic manifestations. Inflammatory bowel-associated pulmonary disease is one of the less commonly recognized and more recently described manifestations. Here, we report the experience of our patients with inflammatory bowel-associated bronchiectasis.

Methods

A retrospective analysis of case notes of patients with IBD and respiratory manifestations was undertaken. Relevant demographic, clinical, radiological, and pulmonary physiology laboratory results were reviewed.

Results

Ten patients with IBD and bronchiectasis were identified. Eight developed respiratory symptoms after surgery for IBD. Five of the ten had ulcerative colitis. Their lung function abnormality is mild to moderate in severity. Small airways disease (forced expiratory flow between 25–75% is <50%) was evident in seven of the ten patients.

Conclusions

This preliminary study supports an association between surgery for IBD and development of symptomatic lung disease, particularly bronchiectasis, in susceptible patients. The pulmonary manifestations of IBD in some patients may only become clinically significant after surgery and the withdrawal of medical treatment.

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Authors and Affiliations

  1. Canterbury Respiratory Research Group, Department of Surgery, Christchurch Hospital, Private Bag 4710, Christchurch, 8001, New Zealand

    Michael G. Kelly, Peter T. Thornley, Lutz Beckert & Michael Epton

  2. Colorectal Unit, Department of Surgery, Christchurch Hospital, Private Bag 4710, Riccarton Ave, Christchurch, 8001, New Zealand

    Frank A. Frizelle & A. Craig Lynch

Authors
  1. Michael G. Kelly
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  2. Frank A. Frizelle
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  3. Peter T. Thornley
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  4. Lutz Beckert
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  5. Michael Epton
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  6. A. Craig Lynch
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Corresponding author

Correspondence to Frank A. Frizelle.

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Kelly, M.G., Frizelle, F.A., Thornley, P.T. et al. Inflammatory bowel disease and the lung: is there a link between surgery and bronchiectasis?. Int J Colorectal Dis 21, 754–757 (2006). https://doi.org/10.1007/s00384-006-0094-9

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  • DOI: https://doi.org/10.1007/s00384-006-0094-9

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