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Factors that influence lower urinary tract symptom (LUTS)-related quality of life (QoL) in a healthy population

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Abstract

Objectives

The aim of this study was to evaluate the factors affecting the lower urinary tract symptoms (LUTS) related quality of life (QoL) score.

Methods

This retrospective study analyzed 29,123 men who underwent health check-ups from January 2007 to July 2011 at a single institution. Those patients who completed the American urologic association symptom index (AUA-SI) with QoL, beck depression inventory (BDI) and state-trait anxiety inventory questionnaires were included in the study. Men with a history of medication for LUTS were excluded from the study. Men who submitted QoL scores of 3 or higher in spite of mild LUTS (total AUA-SI score <8) were defined as having a relatively worse QoL.

Results

Mean age of 21,390 men was 48.4 ± 9.5 years. Mean total AUA-SI score was 6.4 ± 5.9 points. The QoL score was well correlated with the total AUA-SI score (r = 0.705, p < 0.001). Among all AUA-SI items, AUA-SI item 1 (incomplete emptying, r = 0.600, p < 0.001) had the strongest correlation with QoL scores. On the multivariate analysis, hypertension, total AUA-SI score, BDI score, and trait anxiety score were found to be independent factors that influenced the QoL scores. A lower age, a higher PSA, a higher AUA-SI score and a higher BDI score were risk factors for relatively worse QoL scores in spite of mild LUTS.

Conclusions

Among the seven items of AUA-SI, AUA-SI item 1 has the strongest correlation with a worse LUTS-related QoL. Psychological status also influences the QoL scores.

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Author information

Authors and Affiliations

  1. Department of Urology, Konkuk University School of Medicine, Seoul, Korea

    Woo Suk Choi

  2. Department of Internal Medicine, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, Korea

    Nam Ju Heo

  3. Department of Urology, Seoul National University Hospital, Seoul, Korea

    Young Ju Lee

  4. Department of Urology, Seoul National University Boramae Hospital, Sindaebang 2-dong, Dongjak-gu, Seoul, 156-707, Korea

    Hwancheol Son

Authors
  1. Woo Suk Choi
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  2. Nam Ju Heo
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  3. Young Ju Lee
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  4. Hwancheol Son
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Contributions

WSC: Protocol/project development, Data Collection, Data management, Data Analysis, Manuscript writing. NJH: Data Collection. YJL: Manuscript editing. HS: Protocol/project development, Data Collection, Data Analysis.

Corresponding author

Correspondence to Hwancheol Son.

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All authors read and approved the final version of the manuscript.

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For this type of study, formal consent is not required.

Conflict of interest

The authors declare that they have no conflict of interest.

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Choi, W.S., Heo, N.J., Lee, Y.J. et al. Factors that influence lower urinary tract symptom (LUTS)-related quality of life (QoL) in a healthy population. World J Urol 35, 1783–1789 (2017). https://doi.org/10.1007/s00345-017-2052-2

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  • DOI: https://doi.org/10.1007/s00345-017-2052-2

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