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MR-guided percutaneous biopsy of solitary pulmonary lesions using a 1.0-T open high-field MRI scanner with respiratory gating

  • Interventional
  • Published:
European Radiology Aims and scope Submit manuscript

Abstract

Objectives

To prospectively evaluate the feasibility, safety and accuracy of MR-guided percutaneous biopsy of solitary pulmonary lesions using a 1.0-T open MR scanner with respiratory gating.

Methods

Sixty-five patients with 65 solitary pulmonary lesions underwent MR-guided percutaneous coaxial cutting needle biopsy using a 1.0-T open MR scanner with respiratory gating. Lesions were divided into two groups according to maximum lesion diameters: ≤2.0 cm (n = 31) and >2.0 cm (n = 34). The final diagnosis was established in surgery and subsequent histology. Diagnostic accuracy, sensitivity and specificity were compared between the groups using Fisher’s exact test.

Results

Accuracy, sensitivity and specificity of MRI-guided percutaneous pulmonary biopsy in diagnosing malignancy were 96.9 %, 96.4 % and 100 %, respectively. Accuracy, sensitivity and specificity were 96.8 %, 96.3 % and 100 % for lesions 2.0 cm or smaller and 97.1 %, 96.4 % and 100 %, respectively, for lesions larger than 2.0 cm. There was no significant difference between the two groups (P > 0.05). Biopsy-induced complications encountered were pneumothorax in 12.3 % (8/65) and haemoptysis in 4.6 % (3/65). There were no serious complications.

Conclusions

MRI-guided percutaneous biopsy using a 1.0-T open MR scanner with respiratory gating is an accurate and safe diagnostic technique in evaluation of pulmonary lesions.

Key Points

• MRI-guided percutaneous lung biopsy using a 1.0-T open MR scanner is feasibility.

• 96.9 % differentiation accuracy of malignant and benign lung lesions is possible.

• No serious complications occurred in MRI-guided lung biopsy.

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Acknowledgments

The scientific guarantor of this publication is Chengli Li. The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article. This study received funding from the Shandong Science and Technology development plan (2014GGH218005). All authors kindly provided statistical advice for this manuscript. No complex statistical methods were necessary for this paper. Institutional Review Board approval was obtained. Written informed consent was obtained from all subjects (patients) in this study. Methodology: prospective, diagnostic or prognostic study, performed at one institution.

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Authors and Affiliations

  1. Department of Interventional MRI, Shandong Medical Imaging Research Institute affiliated to Shandong University, Shandong Key Laboratory of Advanced Medical Imaging Technologies and Applications, Jinan, Shandong, People’s Republic of China

    Ming Liu, Jie Huang, Yujun Xu, Xiangmeng He, Yubo Lü, Qiang Liu & Chengli Li

  2. Department of Interventional Radiology, Qingdao Central Hospital, Qingdao, Shandong, People’s Republic of China

    Lei Li

  3. The South Western Finland Imaging Centre, Turku University Hospital, Turku, Finland

    Roberto Blanco Sequeiros

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  1. Ming Liu
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  2. Jie Huang
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  4. Xiangmeng He
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  5. Lei Li
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  9. Chengli Li
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Correspondence to Chengli Li.

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Liu, M., Huang, J., Xu, Y. et al. MR-guided percutaneous biopsy of solitary pulmonary lesions using a 1.0-T open high-field MRI scanner with respiratory gating. Eur Radiol 27, 1459–1466 (2017). https://doi.org/10.1007/s00330-016-4518-9

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  • DOI: https://doi.org/10.1007/s00330-016-4518-9

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