Abstract
Objective
The aim of this study was to evaluate the efficacy of home treatment with mud compresses for the hands of patients with rheumatoid arthritis (RA).
Methods
Forty-five patients suffering from RA were enrolled in a double-blind, randomized, controlled study. Twenty-two were treated with true mud compresses (treatment group) and 23 were treated with attenuated mud compresses (control group). The compresses were applied in the patients’ homes five times a week during a 3-week period. Patients were assessed four times: at baseline, upon completion of the 3-week treatment period, 1 month after the treatment, and 3 months after conclusion of the treatment period. Positive response was defined as reductions of 30% or more in the number of tender and swollen joints, 20% or more in physician global assessment of disease activity, and 20% or more in patient global assessment of the severity of joint pain.
Results
In the treatment group, significant reductions in the number of swollen and tender joints and patients’ global assessments of pain severity was observed at all post-treatment assessments. Significant improvement in the scores of physician global assessment was seen at the end of therapy and 1 month later. In the control group, no improvement in the number of swollen and tender joints or physician global assessment was found in any post-treatment evaluation. However, a significant reduction in patient global assessment of joint pain severity was reported at the end of therapy and 3 months after concluding treatment.
Conclusion
Treatment with mud compresses relieves pain affecting the hands and reduces the number of swollen and tender joints in the hands of patients suffering from RA. This treatment can augment conventional medical therapy in these patients.
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References
Sukenik S, Buskila D, Neumann L, Kleiner-Baumgarten A, Zimlichman S, Horowitz J (1990) Sulphur bath and mud pack treatment for rheumatoid arthritis at the Dead Sea area. Ann Rheum Dis 49:99–102
Sukenik S, Neumann L, Buskila D, Kleiner-Baumgarten A, Zimlichman S, Horowitz J (1990) Dead Sea bath salts for the treatment of rheumatoid arthritis. Clin Exp Rheumatol 8:353–357
Sukenik S, Buskila D, Neumann L, Kleiner-Baumgarten A (1992) Mud pack therapy in rheumatoid arthritis. Clin Rheumatol 11:243–247
Elkayam O, Wigler I, Tishler M, Rosenblum I, Caspi D, Segal R et al (1991) Effect of spa therapy in Tiberias on patients with rheumatoid arthritis and osteoarthritis. J Rheumatol 18:1799–1803
Wigler I, Elkayam O, Paran D, Yaron M(1995) Spa therapy for gonarthrosis: a prospective study. Rheumatol Int 15:65–68
Sukenik S, Giryes H, Halevy S, Neumann L, Flusser D, Buskila D (1994) Treatment of psoriatic arthritis at the Dead Sea. J Rheumatol 21:1305–1309
Sukenik S, Baradin R, Codish S, Neumann L, Flusser D, Abu-Shakra D et al (2001) Balneotherapy at the Dead Sea area for patients with psoriatic arthritis and concomitant fibromyalgia. Isr Med Assoc J 3:147–150
Flusser D, Abu-Shakra M, Friger M, Codish S, Sukenik S (2002) Therapy with mud compresses for knee osteoarthritis: comparison of natural mud preparation with mineral-depleted mud. J Clin Rheumatol 8:197–203
Altman R, Asch E, Bloch D, Bole G, Borenstein D, Brandt K et al (1986) Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum 29:1039–1049
Motulsky H (1995) Intuitive biostatistics. Oxford University Press, New York
Sukenik S, Neumann L, Flusser D, Kleiner-Baumgarten A, Buskila D (1995) Balneotherapy for rheumatoid arthritis at the Dead Sea. Isr J Med Sci 31:210–214
Galzigna L, Ceschi-Berrini C, Moschin E, Tolomio C (1998) Thermal mud-pack as an anti-inflammatory treatment. Biomed Pharmacother 52:408–409
Jezova D, Vigas M, Tatar P, Jurcovicova J, Palat M (1985) Rise in plasma beta-endorphin and ACTH in response to hyperthermia in sauna. Horm Metab Res 17:693–694
Pizzoferrato A, Garzia I, Cenni E, Pratelli L, Tarabusi C (2000) Beta-endorphin and stress hormones in patients affected by osteoarthritis undergoing thermal mud therapy [Italian]. Minerva Med 91:239–245
Bellometti S, Giannini S, Sartori L, Crepaldi G (1997) Cytokine levels in osteoarthrosis patients undergoing mud bath therapy. Int J Clin Pharmacol Res 17:149–153
Bellometti S, Cecchettin M, Galzigna L (1997) Mud pack therapy in osteoarthrosis. Changes in serum levels of chondrocyte markers. Clin Chim Acta 268:101–106
Bellometti S, Galzigna L(1998) Serum levels of a prostaglandin and a leukotriene after thermal mud pack therapy. J Investig Med 46:140–145
Bellometti S, Cecchettin M, Lalli A, Galzigna L(1996) Mud pack treatment increases serum antioxidant defenses in osteoarthrotic patients. Biomed Pharmacother 50:37
Niedermeier W, Griggs JH (1971) Trace metal composition of synovial fluid and blood serum of patients with rheumatoid arthritis. J Chronic Dis 23:527–536
Morgenstern H, Machtey I (1983) Serum zinc and copper levels in rheumatoid arthritis. Arthritis Rheum 26:933–934
Svenson KL, Hallgren R, Johansson E, Lindh U (1985) Reduced zinc in peripheral blood cells from patients with inflammatory connective tissue diseases. Inflammation 9:189–199
Shani J, Barak S, Levi D, Ram M, Schachner ER, Schlesinger T et al (1985) Skin penetration of minerals in psoriatics and guinea pigs bathing in hypertonic salt solutions. Pharmacol Res Commun 17:501–512
Acknowledgement
This study was supported in part by a grant from the Ahava Company, Dead Sea Laboratories, Israel.
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Codish, S., Abu-Shakra, M., Flusser, D. et al. Mud compress therapy for the hands of patients with rheumatoid arthritis. Rheumatol Int 25, 49–54 (2005). https://doi.org/10.1007/s00296-003-0402-4
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DOI: https://doi.org/10.1007/s00296-003-0402-4