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Akardius oder “Twin-Reversed-Arterial-Perfusion”-Sequenz Bericht über 4 Geminigraviditäten und Übersicht über den aktuellen Stand der therapeutischen Möglichkeiten

Bericht über 4 Geminigraviditäten und Übersicht über den aktuellen Stand der therapeutischen Möglichkeiten

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Zusammenfassung

Beschrieben werden 4 Acardii aus 2 Obduktionsgute (1 Acardius anceps “Hemiacardius”, 2 Acardii acephali, 1 Acardius amorphus). Es wird auf den aktuellen Stand der Behandlungsmöglichkeiten (Amniozentese bzw. Kontrolle der Fruchtwassermenge durch Indomethacin, Digitalisierung, selektive Geburtseinleitung, Unterbrechen der Anastomosen durch thrombogene Spiralen, sklerosierende Stoffe, Nabelschnurligatur, Laserkoagulation, Thermokoagulation) hingewiesen.

Abstract

We describe four cases of acardius (one of hemiacardius, two of holoacardius acephalus, and one of holacardius amorphus) and present the current range of therapeutic possibilities: control of amniotic fluid by repeated amniocentesis or indomethacin therapy, administration of digoxin to the mother, selective preterm delivery of the acardiac twin by hysterotomy, interruption of the anastomoses by injection of thrombogenic coils, sclerosing agents, umbilical cord ligation, fetoscopic laser coagulation, and thermocoagulation.

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Authors and Affiliations

  1. Pathologisches Institut, Universität Heidelberg, , , , , , DE

    C. Sergi, P.A. Schnabel, S. Adam, B. Krempien & H.F. Otto

  2. Frauenklinik, Universität Heidelberg, , , , , , DE

    E.M. Grischke

  3. Institut für Pathologie, Akademisches Lehrkrankenhaus Pforzheim, Pforzheim, , , , , , DE

    F. Sippel

Authors
  1. C. Sergi
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  2. E.M. Grischke
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  3. P.A. Schnabel
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  4. F. Sippel
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  5. S. Adam
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  6. B. Krempien
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  7. H.F. Otto
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Sergi, C., Grischke, E., Schnabel, P. et al. Akardius oder “Twin-Reversed-Arterial-Perfusion”-Sequenz Bericht über 4 Geminigraviditäten und Übersicht über den aktuellen Stand der therapeutischen Möglichkeiten. Pathologe 21, 308–314 (2000). https://doi.org/10.1007/s002920000372

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  • DOI: https://doi.org/10.1007/s002920000372

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