Abstract
Chronic myelomonocytic leukemia is a myeloid stem cell disease characterized by an abnormal production and accumulation of monocytic cells in association with other signs of myeloproliferation. Extramedullary manifestations of CMML are common and can affect the spleen, liver skin, and lymph nodes. However, otologic manifestations are extremely rare and could have occurred from either direct leukemic infiltration, hemorrhage of the cochlea, labyrinth, leukostasis, or infection. There is no standard treatment protocol for sensorineural hearing loss in CMML patients. More research is needed to improve the understanding of the pathogenesis of this condition, in order to provide better treatment options.
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03 November 2023
A Correction to this paper has been published: https://doi.org/10.1007/s00277-023-05524-8
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RB wrote the manuscript.
MEN corrected and approved the manuscript and provided figures.
YA read and approved manuscript.
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
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MEN reports stock ownership in 3M, Amgen, Johnson & Johnson, Medtronic, and Pfizer.
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The original version of this article was revised: This article was originally published with the name of one of the co-authors was inadvertently misspelled. The incorrect spelling "Marc Ellie-Nader" should be corrected to "Marc-Elie Nader."
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Babakhanlou, R., Nader, ME. & Alvarado, Y. A case of sudden hearing loss in a patient with chronic myelomonocytic leukemia. Ann Hematol 102, 3427–3430 (2023). https://doi.org/10.1007/s00277-023-05433-w
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DOI: https://doi.org/10.1007/s00277-023-05433-w