Skip to main content
Log in

One disease, two faces: clonally-related AML and MPDCP with skin involvement

  • Letter to the Editor
  • Published:
Annals of Hematology Aims and scope Submit manuscript

A Correction to this article was published on 27 December 2023

This article has been updated

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Data availability

No data are available for this manuscript. Medical reports for this case are available upon reasonable request.

Change history

References

  1. Feng J, Pucella JN, Jang G et al (2022) Clonal lineage tracing reveals shared origin of conventional and plasmacytoid dendritic cells. Immunity 55(3):405-422.e11. https://doi.org/10.1016/j.immuni.2022.01.016

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Cella M, Jarrossay D, Facchetti F, Alebardi O, Nakajima H, Lanzavecchia A, Colonna M (1999) Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon. Nat Med 5(8):919–23. https://doi.org/10.1038/11360

    Article  CAS  PubMed  Google Scholar 

  3. El Hussein S, Wang W (2023) Plasmacytoid dendritic cells in the setting of myeloid neoplasms: diagnostic guide to challenging pathologic presentations. Br J Haematol Published online. https://doi.org/10.1111/bjh.18632

    Article  Google Scholar 

  4. Arber DA, Orazi A, Hasserjian RP et al (2022) International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data. Blood 140(11):1200–1228. https://doi.org/10.1182/blood.2022015850

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Khoury JD, Solary E, Abla O et al (2022) The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms. Leukemia 36(7):1703–1719. https://doi.org/10.1038/s41375-022-01613-1

  6. Gong X, Li C, Wang Y et al (2022) Mature plasmacytoid dendritic cells associated with acute myeloid leukemia show similar genetic mutations and expression profiles to leukemia cells. Blood Science 4(1):38–43. https://doi.org/10.1097/BS9.0000000000000097

    Article  PubMed  PubMed Central  Google Scholar 

  7. Zalmaï L, Viailly PJ, Biichle S et al (2020) Plasmacytoid dendritic cells proliferation associated with acute myeloid leukemia: phenotype profile and mutation landscape. Haematologica 106(12):3056–3066. https://doi.org/10.3324/haematol.2020.253740

    Article  CAS  PubMed Central  Google Scholar 

  8. Brunetti L, di Battista V, Venanzi A et al (2017) Blastic plasmacytoid dendritic cell neoplasm and chronic myelomonocytic leukemia: a shared clonal origin. Leukemia 31(5):1238–1240. https://doi.org/10.1038/leu.2017.38

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Contributions

G.C. and G.M. collected the data and wrote the manuscript; M.C., G.P., V.C., S.S., and M.Q. contributed to the clinical management of the patient and discussion of data; E.T, A.V. and C.Ma. performed NGS analysis on bone marrow and skin samples. C.Ma. performed NGS analysis; S.A., C.Me., and M.P.M. coordinated the work, reviewed data, and wrote the manuscript. All authors reviewed and approved the final version of the manuscript.

Corresponding authors

Correspondence to Giovanni Martino or Maria Paola Martelli.

Ethics declarations

Ethics approval

N/A.

Patient consent

Patient’s written consent to the publication of this case has been obtained.

Conflict of interest

MPM declares honoraria from Rasna Therapeutics, Inc. for scientific advisor activities and honoraria/consultancy at scientific advisory board for Abbvie, Amgen, Celgene, Janssen, Novartis, Pfizer, and Jazz Pharmaceuticals. The other authors have no COI to disclose. ET and AV, as the other authors, have no COI to disclose.

Permission to reproduce material from other sources

N/A.

Clinical trial registration

N/A.

Additional information

Publisher's note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Giovanni Martino and Gaetano Cimino are co-first contributors.

Stefano Ascani, Cristina Mecucci, and Maria Paola Martelli are co-last contributors.

The original version of this article was revised: This article was originally published with incomplete authors Prof. Enrico Tiacci and Dr. Alessandra Venanzi.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Martino, G., Cimino, G., Caridi, M. et al. One disease, two faces: clonally-related AML and MPDCP with skin involvement. Ann Hematol 102, 2969–2971 (2023). https://doi.org/10.1007/s00277-023-05377-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00277-023-05377-1

Navigation