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Radiation Exposure During Transarterial Chemoembolization: Angio-CT Versus Cone-Beam CT

  • Clinical Investigation
  • Imaging
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Abstract

Introduction

Cone-beam computed tomography (CBCT) has been developed to improve reliability of many interventional radiology (IR) procedures performed with Angio system, such as transarterial chemoembolization (TACE). Angio-CT has emerged as a new imaging technology that combines a CT scanner with an Angio system in the same IR suite. The purpose of our study was to compare Angio system with CBCT capability and Angio-CT in terms of patient radiation exposure during TACE procedures.

Materials and Methods

Consecutive TACE procedures performed between January 2016 and September 2017 with the two imaging modalities (Artis Zeego defining the CBCT group and Infinix-i 4D-CT defining the Angio-CT group) were reviewed. TACE and patient’s characteristics and patient radiation exposure parameters were collected. Dose-area products (DAP) and dose-length products (DLP) were converted into effective doses (ED) using conversion factors. Accuracy of tumor targeting and response was retrospectively assessed.

Results

A total of 114 TACE procedures in 96 patients were included with 57 procedures in each group. The total ED in the Angio-CT group was 2.5 times lower than that in the CBCT group (median 15.4 vs. 39.2 mSv, p < 0.001). Both 2D ED and 3D ED were lower in the Angio-CT group than in the CBCT group (5.1 vs. 20 mSv, p < 0.001, and 7.4 vs. 17.9 mSv, p < 0.001, respectively). There was no significant difference neither in terms of classes of tumor targeting (p = 0.509) nor in terms of classes of tumor response (p = 0.070) between both groups.

Conclusion

Angio-CT provides significant decrease in patient effective dose during TACE procedures compared to Angio system with CBCT.

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Authors and Affiliations

  1. Department of Radiology, St-Eloi Hospital, CHU Montpellier, University of Montpellier, 80 Avenue Augustin Fliche, 34295, Montpellier, France

    Lauranne Piron, Christophe Cassinotto, Julien Delicque, Ali Belgour, Carole Allimant & Boris Guiu

  2. Department of Medical Physics, CHU Montpellier, Montpellier, France

    Julien Le Roy

  3. Department of Radiology, CHU Nimes, University of Montpellier, Nimes, France

    Jean-Paul Beregi & Joel Greffier

  4. IMAG, CNRS, University of Montpellier, CHU Montpellier, Montpellier, France

    Nicolas Molinari

  5. INSERM U1194, Montpellier Cancer Research Institute, Montpellier, France

    Boris Guiu

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Correspondence to Lauranne Piron.

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Boris Guiu has received honorarium from Canon Medical System for symposium lectures during ECIO, CIRSE, ECR meetings. There is no other relationship to disclose.

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Piron, L., Le Roy, J., Cassinotto, C. et al. Radiation Exposure During Transarterial Chemoembolization: Angio-CT Versus Cone-Beam CT. Cardiovasc Intervent Radiol 42, 1609–1618 (2019). https://doi.org/10.1007/s00270-019-02269-8

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