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Evaluation of a New Esophageal Stent for the Treatment of Malignant and Benign Esophageal Strictures

  • Clinical Investigation
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Abstract

Purpose

To evaluate the efficacy and safety of the EGIS esophageal stent for treating malignant and benign esophageal strictures.

Materials and Methods

Data of 73 patients (mean age 63.0 ± 11.9 years; 66 males) with malignant esophageal stricture and 16 patients (mean age 63.7 ± 9.5 years; 13 males) with benign esophageal stricture who received the EGIS esophageal stent (S&G Biotech, Seongnam, Korea) between October 2010 and April 2016 were obtained from a prospectively maintained electronic database.

Results

Technical and clinical success rates were 100% (89/89). Stent malfunction (i.e., tumor/tissue overgrowth, stent migration, and food impaction) occurred in 20.5% (15/73) and 37.5% (6/16) of patients with malignant and benign esophageal strictures, respectively. Stent migration occurred in five (6.8%) and four (25%) patients with malignant and benign esophageal strictures, respectively. The median follow-up durations in patients with malignant and benign esophageal strictures were 130 [interquartile range (IQR) 76–322] days and 486 (IQR 315–736) days, respectively. Recurrent dysphagia occurred in 14.1% (10/73) and 87.5% (14/16) of patients with malignant and benign esophageal strictures, respectively. The median recurrence-free durations in patients with malignant and benign esophageal strictures were 126 (IQR 69–259) days and 100 (IQR 40–182) days, respectively.

Conclusion

The EGIS esophageal stent appears to be effective for malignant esophageal strictures, with relatively low rate of stent migration, whereas, for benign esophageal strictures, it seems to be associated with a high rate of recurrent dysphagia, mainly due to stent migration.

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Acknowledgements

This study was supported by a grant of the Korean Health Technology R&D Project, Ministry of Health & Welfare, Republic of Korea (Grant Number: HI15C0484 to H.Y.S.).

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Author notes

  1. Kun Yung Kim and Jiaywei Tsauo have contributed equally to this work.

Authors and Affiliations

  1. Departments of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olymic-ro 43-gil, Songpa-Gu, Seoul, 138-736, Republic of Korea

    Kun Yung Kim, Jiaywei Tsauo, Ho-Young Song, Jung-Hoon Park, Eun Jung Jun, Wei-Zhong Zhou & Min Tae Kim

  2. Biomedical Engineering Center, Asan Institute for Life Sciences, University of Ulsan College of Medicine, Songpa-Gu, Seoul, 138-736, Republic of Korea

    Jung-Hoon Park

  3. Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China

    Wei-Zhong Zhou

Authors
  1. Kun Yung Kim
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  2. Jiaywei Tsauo
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Corresponding author

Correspondence to Ho-Young Song.

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Conflict of interest

All authors declare that there is no conflict of interest.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

This retrospective study was approved by our institutional review board, and the requirement for written informed consent was waived.

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Kim, K.Y., Tsauo, J., Song, HY. et al. Evaluation of a New Esophageal Stent for the Treatment of Malignant and Benign Esophageal Strictures. Cardiovasc Intervent Radiol 40, 1576–1585 (2017). https://doi.org/10.1007/s00270-017-1677-2

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  • DOI: https://doi.org/10.1007/s00270-017-1677-2

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