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Role of magnetic resonance imaging to differentiate between borderline and malignant serous epithelial ovarian tumors

  • Special Section: Quantitative Imaging
  • Published:
Abdominal Radiology Aims and scope Submit manuscript

Abstract

Purpose

We aimed to differentiate serous borderline ovarian tumors (SBOT) from serous epithelial ovarian carcinomas (SEOC) using morphological and functional MRI findings, to improve the patient management.

Method

We retrospectively investigated 24 ovarian lesions diagnosed with SBOT and 64 ovarian lesions diagnosed with SEOC. Additional to the demographic and morphological findings T2W signal intensity ratio, mean apparent diffusion coefficient (ADCmean) and total apparent diffusion coefficient (ADCtotal) values were analyzed and compared between two groups.

Results

Bilaterality, pelvic free fluid presence, serum CA-125 level (U/mL), presence of pelvic peritoneal implant were in favor of SEOC. Lower maximum size of solid component and solid size to maximum size ratio, dominantly cystic and solid-cystic appearance, exophytic growth pattern, presence of papiller projection and papillary architecture and internal branching pattern, higher T2W signal intensity ratio, ADCmean and ADCtotal values were in favor of SBOT.

Conclusion

Our study revealed that morphological and functional imaging findings were valuable in differentiating BSOT from SEOC.

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Authors and Affiliations

  1. Department of Radiology, Faculty of Medicine, Bezmialem Vakif University, +34093, Istanbul, Turkey

    Ahmet Akçay, Abdusselim Adil Peker, Zeynep Oran, Hüseyin Toprak, Serdar Balsak, Bahar Atasoy Badur & Mehmet Ali Gültekin

  2. Department of Biostatistics, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey

    Özlem Toluk

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  1. Ahmet Akçay
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  2. Abdusselim Adil Peker
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Correspondence to Ahmet Akçay.

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The authors have no relevant fnancial or nonfnancial interests to disclose.

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This study was conducted in accordance with the principles of the Declaration of Helsinki. This study was approved by the Research Ethics Committee (Approval Number: 54022451-050.05.04-11445).

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Informed consent had been obtained from all patients before surgery and specimen sampling were conducted.

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Akçay, A., Peker, A.A., Oran, Z. et al. Role of magnetic resonance imaging to differentiate between borderline and malignant serous epithelial ovarian tumors. Abdom Radiol 49, 229–236 (2024). https://doi.org/10.1007/s00261-023-04076-9

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  • DOI: https://doi.org/10.1007/s00261-023-04076-9

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