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Discrimination of serous cystadenoma from mucinous cystic neoplasm and branch duct intraductal papillary mucinous neoplasm in the pancreas with CT

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Abstract

Purpose

The imaging features of serous cystadenomas (SCAs) overlap with those of mucinous cystic neoplasms (MCNs) and branch duct intraductal papillary mucinous neoplasms (BD-IPMNs), and an accurate preoperative diagnosis is important for clinical treatment due to their different biological behaviors. The aim of this study was to provide a computed tomographic (CT) feature for the diagnosis of SCAs and estimate whether the “circumvascular sign” can contribute to the discrimination of SCAs from MCNs and BD-IPMNs.

Methods

From August 2011 through December 2019, a total of 71 patients (30 patients with 30 SCAs, 21 patients with 21 MCNs and 20 patients with 22 BP-IPMNs) were enrolled in this study. All patients underwent CT examination and were confirmed by surgical pathology. In addition to patient clinical information, CT features (e.g., location, shape) were evaluated via CT.

Results

Central scarring, central calcification and the circumvascular sign were found to be specific CT features for the diagnosis of SCAs and their differential diagnosis from MCNs and BD-IPMNs. All three CT features had high specificity, and both central scarring and central calcification had low sensitivity. When any one of these two features was combined with the circumvascular sign, the sensitivity increased to 83.3%.

Conclusion

Pancreatic cystic neoplasms that show central scarring, central calcification or the circumvascular sign on CT could be diagnosed as SCAs. When either of the first two features is combined with the circumvascular sign, the diagnostic sensitivity could be increased.

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Authors and Affiliations

  1. Department of Radiology, Xinqiao Hospital, Third Military Medical University, Chongqing, 400037, China

    Guang-xian Wang, Zhi-ping Wang, Dong Zhang & Li Wen

  2. Department of Pathology, Xinqiao Hospital, Third Military Medical University, Chongqing, 400037, China

    Hai-ling Chen

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  1. Guang-xian Wang
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  2. Zhi-ping Wang
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  3. Hai-ling Chen
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  4. Dong Zhang
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Correspondence to Li Wen.

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Wang, Gx., Wang, Zp., Chen, Hl. et al. Discrimination of serous cystadenoma from mucinous cystic neoplasm and branch duct intraductal papillary mucinous neoplasm in the pancreas with CT. Abdom Radiol 45, 2772–2778 (2020). https://doi.org/10.1007/s00261-020-02664-7

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  • DOI: https://doi.org/10.1007/s00261-020-02664-7

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