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Ultrasound-guided renal transplant biopsy: practical and pragmatic considerations

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A Correction to this article was published on 07 December 2018

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Abstract

Sonographically guided percutaneous core biopsy of renal allografts has been performed for decades, providing valuable information in monitoring the status of normally functioning renal transplants as well as investigating the cause of renal transplant dysfunction. This article reviews practical aspects of biopsy technique using the cortical tangential approach, with consideration of factors that may influence biopsy success, including selection of biopsy device. Clinically important complications from renal transplant biopsy are uncommon; the most recent experience for one institution is analyzed in the context of existing evidence regarding the frequency and timing of these major complications, to understand pragmatic implications for peri-procedural care.

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Change history

  • 07 December 2018

    The original version of this article unfortunately contained an error. Though one of the coauthor names correctly appeared in the published version, it is incorrectly displayed in indexing sites due to a tagging error in metadata.

  • 07 December 2018

    The original version of this article unfortunately contained an error. Though one of the coauthor names correctly appeared in the published version, it is incorrectly displayed in indexing sites due to a tagging error in metadata.

References

  1. Racusen LC, Solez K, Colvin RB, et al. (1999) The Banff 97 working classification of renal allograft pathology. Kidney Int 55(2):713–723

    Article  CAS  PubMed  Google Scholar 

  2. Solez K, Colvin RB, Racusen LC, et al. (2008) Banff 07 classification of renal allograft pathology: updates and future directions. Am J Transplant 8(4):753–760. https://doi.org/10.1111/j.1600-6143.2008.02159.x

    Article  CAS  PubMed  Google Scholar 

  3. Patel MD, Phillips CJ, Young SW, et al. (2010) US-guided renal transplant biopsy: efficacy of a cortical tangential approach. Radiology 256(1):290–296

    Article  PubMed  Google Scholar 

  4. Boban MD, Tiefenthaler M (2017) Tangential extraperitoneal retrorenal approach: a specified uniform technique for renal transplant biopsy. Transpl Int 30(9):947–950. https://doi.org/10.1111/tri.12994

    Article  PubMed  Google Scholar 

  5. Nicholson ML, Wheatley TJ, Doughman TM, et al. (2000) A prospective randomized trial of three different sizes of core-cutting needle for renal transplant biopsy. Kidney Int 58(1):390–395

    Article  CAS  PubMed  Google Scholar 

  6. Haggarth L, Ekman P, Egevad L (2002) A new core-biopsy instrument with an end-cut technique provides prostate biopsies with increased tissue yield. BJU Int 90(1):51–55

    Article  CAS  PubMed  Google Scholar 

  7. Moore JZ, McLaughlin PW, Shih AJ (2012) Novel needle cutting edge geometry for end-cut biopsy. Med Phys 39(1):99–108. https://doi.org/10.1118/1.3665253

    Article  PubMed  Google Scholar 

  8. Dogan HS, Eskicorapci SY, Ertoy-Baydar D, et al. (2005) Can we obtain better specimens with an end-cutting prostatic biopsy device? Eur Urol 47(3):297–301. https://doi.org/10.1016/j.eururo.2004.09.004

    Article  PubMed  Google Scholar 

  9. Ozden E, Gogus C, Tulunay O, Baltaci S (2004) The long core needle with an end-cut technique for prostate biopsy: does it really have advantages when compared with standard needles? Eur Urol 45(3):287–291. https://doi.org/10.1016/j.eururo.2003.10.004

    Article  PubMed  Google Scholar 

  10. Patel MD, Miranda R, Phillips CJ, et al. (2011) Impact of a quality assessment program on radiologist performance in ultrasound-guided renal transplant biopsy. J Am Coll Radiol 8(5):355–359. https://doi.org/10.1016/j.jacr.2010.08.014

    Article  PubMed  Google Scholar 

  11. Baffour FI, Hickson LJ, Stegall MD, et al. (2017) Effects of aspirin therapy on ultrasound-guided renal allograft biopsy bleeding complications. J Vasc Interv Radiol 28(2):188–194. https://doi.org/10.1016/j.jvir.2016.10.021

    Article  PubMed  Google Scholar 

  12. Furness PN, Philpott CM, Chorbadjian MT, et al. (2003) Protocol biopsy of the stable renal transplant: a multicenter study of methods and complication rates. Transplantation 76(6):969–973

    Article  PubMed  Google Scholar 

  13. Redfield RR, McCune KR, Rao A, et al. (2016) Nature, timing, and severity of complications from ultrasound-guided percutaneous renal transplant biopsy. Transpl Int 29(2):167–172. https://doi.org/10.1111/tri.12660

    Article  PubMed  Google Scholar 

  14. Morgan TA, Chandran S, Burger IM, Zhang CA, Goldstein RB (2016) Complications of ultrasound-guided renal transplant biopsies. Am J Transplant 16(4):1298–1305. https://doi.org/10.1111/ajt.13622

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Radiology, Mayo Clinic Arizona, 5777 E. Mayo Blvd, Phoenix, AZ, 85054, USA

    Maitray D. Patel, Scott W. Young, J. Scott Kriegshauser & Nirvikar Dahiya

Authors
  1. Maitray D. Patel
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  2. Scott W. Young
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  3. J. Scott Kriegshauser
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  4. Nirvikar Dahiya
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Corresponding author

Correspondence to Maitray D. Patel.

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This study has no funding.

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The authors declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. For this type of study formal consent is not required.

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Patel, M.D., Young, S.W., Scott Kriegshauser, J. et al. Ultrasound-guided renal transplant biopsy: practical and pragmatic considerations. Abdom Radiol 43, 2597–2603 (2018). https://doi.org/10.1007/s00261-018-1484-5

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  • DOI: https://doi.org/10.1007/s00261-018-1484-5

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