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Nuclear cardiology and heart failure

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Abstract

The prevalence of heart failure in the adult population is increasing. It varies between 1% and 2%, although it mainly affects elderly people (6–10% of people over the age of 65 years will develop heart failure). The syndrome of heart failure arises as a consequence of an abnormality in cardiac structure, function, rhythm, or conduction. Coronary artery disease is the leading cause of heart failure and it accounts for this disorder in 60–70% of all patients affected. Nuclear techniques provide unique information on left ventricular function and perfusion by gated-single photon emission tomography (SPECT). Myocardial viability can be assessed by both SPECT and PET imaging. Finally, autonomic dysfunction has been shown to increase the risk of death in patients with heart disease and this may be applicable to all patients with cardiac disease regardless of aetiology. MIBG scanning has a very promising prognostic value in patients with heart failure.

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Authors and Affiliations

  1. Department of Nuclear Medicine, University of Brescia, Piazza Spedali Civili, 1, 25123, Brescia, Italy

    Raffaele Giubbini & Francesco Bertagna

  2. Nuclear Medicine Unit, Ospedale Di Castelfranco Veneto (Tv), Castelfranco Veneto, Italy

    Elisa Milan

  3. Nuclear Medicine Section, Division of Human Health, International Atomic Energy Agency, Vienna, Austria

    Fernando Mut & Maurizio Dondi

  4. Department of Cardiology, University of Brescia, Brescia, Italy

    Marco Metra

  5. Health Physics Department, Spedali Civili di Brescia, Brescia, Italy

    Carlo Rodella

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  1. Raffaele Giubbini
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  2. Elisa Milan
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  3. Francesco Bertagna
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Correspondence to Raffaele Giubbini.

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This review is a part of the conclusions of the IAEA Technical Meeting “Current Role of Nuclear Cardiology in the Management of Cardiac Diseases” held at the IAEA Headquarters, Vienna, Austria, on 5–9 May 2008.

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Giubbini, R., Milan, E., Bertagna, F. et al. Nuclear cardiology and heart failure. Eur J Nucl Med Mol Imaging 36, 2068–2080 (2009). https://doi.org/10.1007/s00259-009-1246-2

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