References
Alberto R, Ortner K, Wheatley N, Schibli R, Schubiger AP. Synthesis and properties of boranocarbonate: a convenient in situ CO source for the aqueous preparation of [99mTc(OH2)3(CO)3]+. J Am Chem Soc 2001; 123:3135–3136.
Jurisson SS, Lydon JD. Potential technetium small molecule radiopharmaceuticals. Chem Rev 1999; 99:2205–2218.
Schibli R, Schwarzbach R, Alberto R, Ortner K, Schmalle H, Dumas C, Egli A, Schubiger PA. Steps toward high specific activity labeling of biomolecules for therapeutic application: Preparation of precursor [Re-188(H2O)(3)(CO)(3)](+) and synthesis of tailor-made bifunctional ligand systems. Bioconjug Chem 2002; 13:750–756.
Schibli R, Katti KV, Higginbotham C, Volkert WA, Alberto R. In vitro and in vivo evaluation of bidentate, water-soluble phosphine ligands as anchor groups for the organometallic fac-[Tc-99m(CO)(3)](+)-core. Nucl Med Biol 1999; 26:711–716.
Pak JK, Benny P, Spingler B, Ortner K, Alberto R. N functionalization of metal and organic protected L-histidine for a highly efficient, direct labeling of biomolecules with [Tc(OH2)3(CO)3]+. Chem Eur J 2003; 9:2053–2061.
Bernard J, Ortner K, Spingler B, Pietzsch HJ, Alberto R. Aqueous synthesis of derivatized cyclopentadienyl complexes of technetium and rhenium directed toward radiopharmaceutical application. Inorg Chem 2003; 42:1014–1022.
Wald J, Alberto R, Ortner K, Candreia L. Aqueous one-pot synthesis of derivatized cyclopentadienyl-tricarbonyl complexes99mTc with an in situ CO source: application to a serotonergic receptor ligand. Angew Chem Int Ed Engl 2001; 113:3152–3156
Alberto R, Schibli R, Waibel R, Abram U, Schubiger AP. Basic aqueous chemistry of [M(OH2)3(CO)3]+ (M=Re, Tc) directed towards radiopharmaceutical application. Coordin Chem Rev 1999; 192:901–919.
Schibli R, Bella RL, Alberto R, Garcia-Garayoa E, Ortner K, Abram U, Schubiger PA. Influence of the denticity of ligand systems on the in vitro and in vivo behaviour of99mTc(I)-tricarbonyl complexes: a hint for the future functionalization of biomolecules. Bioconjugate Chem 2000; 3:345–351.
Author information
Authors and Affiliations
Corresponding author
Additional information
The opinions expressed within the Controversies section represent the views of the authors only.
Rights and permissions
About this article
Cite this article
Alberto, R. [Tc(CO)3]+ chemistry: a promising new concept for SPET?. Eur J Nucl Med Mol Imaging 30, 1299–1302 (2003). https://doi.org/10.1007/s00259-003-1292-0
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00259-003-1292-0