Abstract
Antrodia camphorata, also known as A. cinnamomea, is a precious medicinal basidiomycete fungus endemic to Taiwan. This article summarizes the recent advances in research on the multifarious pharmacological effects of A. camphorata. The mushroom exhibits anticancer activity toward a large variety of cancers including breast, cervical, ovarian, prostate, bladder, colorectal, pancreatic, liver, and lung cancers; melanoma; leukemia; lymphoma; neuroblastoma; and glioblastoma. Other activities encompass antiinflammatory, antiatopic dermatitis, anticachexia, immunoregulatory, antiobesity, antidiabetic, antihyperlipidemic, antiatherosclerotic, antihypertensive, antiplatelet, antioxidative, antiphotodamaging, hepatoprotective, renoprotective, neuroprotective, testis protecting, antiasthmatic, osteogenic, osteoprotective, antiviral, antibacterial, and wound healing activities. This review aims to provide a reference for further development and utilization of this highly prized mushroom.
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This work was supported by the University-Industry Cooperation Project of Fujian Science and Technology Department (2018N5005). We also gratefully acknowledge the award of HMRF research grant (no. 12131221) from Food and Health Bureau, the Government of Hong Kong Special Administrative Region, and a grant from National Natural Science Foundation of China (no. 81471927).
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Wang, C., Zhang, W., Wong, J.H. et al. Diversity of potentially exploitable pharmacological activities of the highly prized edible medicinal fungus Antrodia camphorata. Appl Microbiol Biotechnol 103, 7843–7867 (2019). https://doi.org/10.1007/s00253-019-10016-9
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DOI: https://doi.org/10.1007/s00253-019-10016-9