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Production and transcriptional regulation of proanthocyanidin biosynthesis in forage legumes

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Abstract

Proanthocyanidins (PA), also known as condensed tannins, contribute to important forage legumes traits including disease resistance and forage quality. PA in forage plants has both positive and negative effects on feed digestibility and animal performance. The analytical methods and their applicability in measuring the contents of PA in forage plants are essential to studies on their nutritional effects. In spite of important breakthroughs in our understanding of the PA biosynthesis, important questions still remain to be answered such as the PA polymerization and transport. Recent advances in the understanding of transcription factor-mediated gene regulation mechanisms in anthocyanin and PA biosynthetic pathway in model plants suggest new approaches for the metabolic engineering of PA in forage plants. The present review will attempt to present the state-of-the-art of research in these areas and provide an update on the production and metabolic engineering of PA in forage plants. We hope that this will contribute to a better understanding of the ways in which PA production to manipulate the content of PA for beneficial effects in forage plants.

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Acknowledgments

This work was supported by the National Natural Science Foundation of China (Grant No. 31372361) and National Program on Key Basic Research Project (973 Program) (Grant No. 2014CB138701).

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Authors and Affiliations

  1. Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Room 211, Zhongguancun South Street No. 12, Haidian District, Beijing, 100081, China

    Meiliang Zhou, Zhanmin Sun, Lihua Gao, Yixiong Tang & Yanmin Wu

  2. State Key Laboratory of Grassland Agro-ecosystems, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, 730020, China

    Li Wei

  3. College of Landscape and Travel, Agricultural University of Hebei, Baoding, Hebei, 071001, China

    Yu Meng

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  1. Meiliang Zhou
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  2. Li Wei
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  3. Zhanmin Sun
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  4. Lihua Gao
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  5. Yu Meng
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  6. Yixiong Tang
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  7. Yanmin Wu
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Correspondence to Yanmin Wu.

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Zhou, M., Wei, L., Sun, Z. et al. Production and transcriptional regulation of proanthocyanidin biosynthesis in forage legumes. Appl Microbiol Biotechnol 99, 3797–3806 (2015). https://doi.org/10.1007/s00253-015-6533-1

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  • DOI: https://doi.org/10.1007/s00253-015-6533-1

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