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Tracheal side effects following fetal endoscopic tracheal occlusion for severe congenital diaphragmatic hernia

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References

  1. Deprest JA, Gratacos E, Nicolaides K et al (2009) Changing perspectives on the perinatal management of isolated congenital diaphragmatic hernia in Europe. Clin Perinatol 36:329–347

    Article  PubMed  Google Scholar 

  2. Harrison MR, Adzick NS, Longaker MT et al (1990) Successful repair in utero of a fetal diaphragmatic hernia after removal of herniated viscera from the left thorax. N Engl J Med 322:1582–1584

    Article  CAS  PubMed  Google Scholar 

  3. DiFiore JW, Fauza DO, Slavin R et al (1994) Experimental fetal tracheal ligation reverses the structural and physiological effects of pulmonary hypoplasia in congenital diaphragmatic hernia. J Pediatr Surg 29:248–256

    Article  CAS  PubMed  Google Scholar 

  4. Nelson S, Cameron A, Deprest JA (2006) Fetoscopic surgery for in utero management of congenital diaphragmatic hernia. Fet Mat Medicine Rev 17:69–104

    Article  Google Scholar 

  5. Flake AW, Crombleholme TM, Johnson MP et al (2000) Treatment of severe congenital diaphragmatic hernia by fetal tracheal occlusion: clinical experience with fifteen cases. Am J Obstet Gynecol 183:1059–1066

    Article  CAS  PubMed  Google Scholar 

  6. Deprest J, Gratacos E, Nicolaides KH, FETO Task Group (2004) Fetoscopic tracheal occlusion (FETO) for severe congenital diaphragmatic hernia: evolution of a technique and preliminary results. Ultrasound Obstet Gynecol 24:121–126

    Article  CAS  PubMed  Google Scholar 

  7. Flageole H, Evrard VA, Piedboeuf B et al (1998) The plug-unplug sequence: an important step to achieve type II pneumocyte maturation in the fetal lamb model. J Pediatr Surg 33:299–303

    Article  CAS  PubMed  Google Scholar 

  8. Jani JC, Nicolaides KH, Gratacós E et al (2009) Severe diaphragmatic hernia treated by fetal endoscopic tracheal occlusion. Ultrasound Obstet Gynecol 34:304–310

    Article  CAS  PubMed  Google Scholar 

  9. Jani J, Nicolaides KH, Keller RL, Antenatal-CDH-Registry Group et al (2007) Observed to expected lung area to head circumference ratio in the prediction of survival in fetuses with isolated diaphragmatic hernia. Ultrasound Obstet Gynecol 30:67–71

    Article  CAS  PubMed  Google Scholar 

  10. Deprest JA, Hyett JA, Flake AW et al (2009) Current controversies in prenatal diagnosis 4: should fetal surgery be done in all cases of severe diaphragmatic hernia. Prenat Diagn 29:15–19

    Article  CAS  PubMed  Google Scholar 

  11. Jani JC, Benachi A, Nicolaides KH, Antenatal CDH Registry group et al (2009) Prenatal prediction of neonatal morbidity in survivors with congenital diaphragmatic hernia: a multicenter study. Ultrasound Obstet Gynecol 33:64–69

    Article  CAS  PubMed  Google Scholar 

  12. Jani J, Nicolaides K, Gratacos E et al (2007) Short term neonatal morbidity in severe left-sided congenital diaphragmatic hernia treated by tracheal occlusion before 30 weeks. Am J Obstet Gynecol 197:S162

    Article  Google Scholar 

  13. Harrison MR, Adzick NS, Flake AW et al (1996) Correction of congenital diaphragmatic hernia in utero VIII: response of the hypoplastic lung to tracheal occlusion. J Pediatr Surg 31:1339–1348

    Article  CAS  PubMed  Google Scholar 

  14. Flageole H, Evrard VA, Vandenberghe K et al (1997) Tracheoscopic endotracheal occlusion in the ovine model: technique and pulmonary effects. J Pediatr Surg 32:1328–1331

    Article  CAS  PubMed  Google Scholar 

  15. Fayoux P, Marciniak B, Devisme L et al (2008) Prenatal and early postnatal morphogenesis and growth of human laryngotracheal structures. J Anat 213:86–92

    Article  PubMed  Google Scholar 

  16. Yamamoto H, Perales A, Delezoide AL et al (2001) Correlation of tracheal diameter measured by ultrasound and necropsy findings in human fetuses. Am J Obstet Gynecol 184:S138–458

    Google Scholar 

  17. Bealer JF, Skarsgard ED, Hedrick MH et al (1995) The ‘PLUG’ odyssey: adventures in experimental fetal tracheal occlusion. J Pediatr Surg 30:361–364

    Article  CAS  PubMed  Google Scholar 

  18. Deprest JA, Evrard VA, Verbeken EK et al (2000) Tracheal side effects of endoscopic balloon tracheal occlusion in the fetal lamb model. Eur J Obstet Gynecol Reprod Biol 92:119–126

    Article  CAS  PubMed  Google Scholar 

  19. Chiba T, Albanese CT, Farmer DL et al (2000) Balloon tracheal occlusion for congenital diaphragmatic hernia: experimental Studies. J Pediatr Surg 35:1566–1570

    Article  CAS  PubMed  Google Scholar 

  20. McHugh K, Afaq A, Broderick N et al (2009) Tracheomegaly: a complication of fetal endoscopic tracheal occlusion in the treatment of congenital diaphragmatic hernia. Pediatr Radiol Nov 6 [Epub ahead of print]

  21. Fayoux P, Hosana G, Devisme L et al (2010) Neonatal tracheal changes following in utero fetoscopic balloon tracheal occlusion (FETO) in severe congenital diaphragmatic hernia (CDH). J Ped Surg (in press)

  22. Cullen AB, Cooke PH, Driska SP et al (2006) The impact of mechanical ventilation on immature airway smooth muscle: functional, structural, histological, and molecular correlates. Biol Neonate 90:17–27

    Article  PubMed  Google Scholar 

  23. Karsh S, Mahboubi S (1989) Tracheomegaly in children. Clin Imaging 13:77–81

    Article  CAS  PubMed  Google Scholar 

  24. EuroSTEC, 6th Framework, LSHC-CT-2006-037409 www.eurostec.eu

  25. American Academy of Surgery Section on Surgery; American Academy of Pediatrics Committee on Fetus and Newborn (2008) Postdischarge follow-up of infants with congenital diaphragmatic hernia. Pediatrics 121:627–632

    Article  Google Scholar 

  26. Harrison MR, Keller RL, Hawgood SB et al (2003) A randomized trial of fetal endoscopic tracheal occlusion for severe fetal congenital diaphragmatic hernia. N Engl J Med 349:1916–1924

    Article  CAS  PubMed  Google Scholar 

  27. Keller RL, Hawgood S, Neuhaus JM et al (2004) Infant pulmonary function in a randomized trial of fetal tracheal occlusion for severe congenital diaphragmatic hernia. Pediatr Res 56:818–825

    Article  PubMed  Google Scholar 

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Acknowledgments

The FETO programme is in part supported by the European Commission (EuroSTEC, 6th Framework, LSHC-CT-2006-037409) and the Flemish Community of Belgium (IWT/ 070715). JDP is a “clinical researcher” of the Fonds voor Wetenschappelijk Onderzoek Vlaanderen (1.8.012.07.N.02). AD is a clinical researcher supported by the KOOR funds of the University Hospitals Leuven.

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  1. Jan Deprest

    Present address: Department Woman and Child, Division Woman, University Hospital Leuven, Herestraat 49, 3000, Leuven, Belgium

Authors and Affiliations

  1. FETO Consortium, Leuven-Barcelona-London

    Jan Deprest, Eduardo Gratacos & Kypros Nicolaides

  2. Hospital Clinic, Barcelona, Spain

    Eduardo Gratacos

  3. King’s College, London, UK

    Kypros Nicolaides

  4. Department Woman and Child, University Hospitals Leuven, Leuven, Belgium

    Jan Deprest, Anne Debeer & Marijke Proesmans

  5. Department Medical Imaging, University Hospitals Leuven, Leuven, Belgium

    Luc Breysem, Filip Claus & Maria Helena Smet

  6. Department of Pediatric Otorhinolaryngology, CHRU Jeanne de Flandre, Lille, France

    Pierre Fayoux

  7. Department Perinatology, CHRU Jeanne de Flandre, Lille, France

    Laurent Storme

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  1. Jan Deprest
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  9. Pierre Fayoux
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  10. Laurent Storme
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Correspondence to Jan Deprest.

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Deprest, J., Breysem, L., Gratacos, E. et al. Tracheal side effects following fetal endoscopic tracheal occlusion for severe congenital diaphragmatic hernia. Pediatr Radiol 40, 670–673 (2010). https://doi.org/10.1007/s00247-010-1579-9

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  • DOI: https://doi.org/10.1007/s00247-010-1579-9

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