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Central nervous system manifestations of HIV infection in children

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Abstract

Vertically transmitted HIV infection is a major problem in the developing world due to the poor availability of antiretroviral agents to pregnant women. HIV is a neurotrophic virus and causes devastating neurological insults to the immature brain. The effects of the virus are further compounded by the opportunistic infections and neoplasms that occur as a result of the associated immune suppression. This review focuses on the imaging features of HIV infection and its complications in the central nervous system.

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Authors and Affiliations

  1. Department of Radiology, Tygerberg Academic Hospital, University of Stellenbosch, Cape Town, South Africa

    Reena George, Savvas Andronikou, Jaco du Plessis, Anne-Marie du Plessis & Arthur Maydell

  2. Department of Paediatrics and Child Health, Tygerberg Academic Hospital, University of Stellenbosch, Cape Town, South Africa

    Ronald Van Toorn

Authors
  1. Reena George
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  2. Savvas Andronikou
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  3. Jaco du Plessis
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  4. Anne-Marie du Plessis
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  5. Ronald Van Toorn
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  6. Arthur Maydell
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Correspondence to Reena George.

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George, R., Andronikou, S., du Plessis, J. et al. Central nervous system manifestations of HIV infection in children. Pediatr Radiol 39, 575–585 (2009). https://doi.org/10.1007/s00247-009-1170-4

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  • DOI: https://doi.org/10.1007/s00247-009-1170-4

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