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Langerhans’ cell histiocytosis of the clivus: case report and literature review

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Abstract

This report describes a 5-year-old girl with Langerhans’ cell histiocytosis (LCH) of the clivus. To date only five patients, including our patient, have been described with LCH at this site. Our patient differs from those previously reported by her atypical clinical presentation with torticollis, but without a sixth nerve palsy. In addition, she is the first patient to present with concomitant disease elsewhere at the time of diagnosis, i.e. both femoral necks and left proximal humerus. Our patient thus presents unique features and underlines the importance of including LCH in the differential diagnosis of erosive lesions of the clivus.

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Authors and Affiliations

  1. Department of Radiology, Our Lady’s Hospital for Sick Children, Crumlin, Dublin 12, Ireland

    Maja E. Hurley & Roisin Hayes

  2. Department of Oncology, Our Lady’s Hospital for Sick Children, Dublin 12, Ireland

    Anne O’Meara

  3. Department of Orthopaedics, Our Lady’s Hospital for Sick Children, Dublin 12, Ireland

    Esmond Fogarty

Authors
  1. Maja E. Hurley
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  2. Anne O’Meara
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  3. Esmond Fogarty
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  4. Roisin Hayes
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Correspondence to Maja E. Hurley.

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Hurley, M.E., O’Meara, A., Fogarty, E. et al. Langerhans’ cell histiocytosis of the clivus: case report and literature review. Pediatr Radiol 34, 267–270 (2004). https://doi.org/10.1007/s00247-003-1065-8

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  • DOI: https://doi.org/10.1007/s00247-003-1065-8

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