Abstract
Transcatheter pulmonary valve implantation (TPVI) is a surgical alternative for correcting dysfunctional right ventricular outflow tract in previously operated patients. MyVal transcatheter heart valve (THV) (Meril Life Sciences, India), a new transcatheter valve designed for aortic position has recently been reported to be implanted in pulmonary position. Myval transcatheter valve were implanted in patients with stenosed dysfunctional conduits, severe regurgitation from transannular patch or dysfunctional surgical pulmonary valves (Bioprosthesis). Procedural details and post-TPVI follow-up were analysed. Myval TPVI was used in Fifty three patients with median age of 15 years (IQR 12–19.5 years). Almost sixty percent of the patients were male, with a median weight of 50 kg (31–63 kg). Prestenting was used in more than 80 percent of patients (n = 45 patients), while 6 patients had a prior surgical valve implantation. After Myval TPVI implantation, the peak instantaneous gradient across the RVOT decreased from a median of 23.5 mmHg (IQR 10–53 mmHg) pre-procedure to 10 mmHg (IQR 5–16 mmHg) post-procedure. The median fluoroscopy time for the procedure was 35 min (IQR 23.5–44 min). The large sizes—mainly the 29-mm and 32 mm Myval (Navigator, Meril Life Sciences Pvt Ltd, India), were the most used size in 40% (n = 22) of the cases each. The median contrast volume used during the procedure was 247 mL (IQR 120–300 mL). Patients were followed for a median period of 360 days (IQR 164–525 days). At the last clinic follow-up, there was no tricuspid valve regurgitation. Moderate neo-pulmonary valve regurgitation was reported in three cases. Early experience of TPVI with MyVal is encouraging with procedural success in all patients and acceptable mid-term outcomes.
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References
Lee C, Park CS, Lee CH, Kwak JG, Kim SJ, Shim WS et al (2011) Durability of bioprosthetic valves in the pulmonary position: long-term follow-up of 181 implants in patients with congenital heart disease. J Thorac Cardiovasc Surg 142(2):351–358
Hascoët S, Acar P, Boudjemline Y (2014) Transcatheter pulmonary valvulation: current indications and available devices. Arch Cardiovasc Dis 107(11):625–634
Sivaprakasam MC, Arvind A, Sridhar A, Gunasekaran S (2020) First transcatheter pulmonary valve implantation—An Indian made valve. IHJ Cardiovasc Case Rep CVCR 4(1):13–16
Odemis E, Yenidogan I (2022) First experiences with Myval transcatheter heart valve system in the treatment of severe pulmonary regurgitation in native right ventricular outflow tract and conduit dysfunction. Cardiol Young 32(10):1609–1615
Sharma SK et al (2020) Myval transcatheter heart valve system in the treatment of severe symptomatic aortic stenosis. Future Cardiol 17:73–80
Sivaprakasam MC, Reddy JRV, Gunasekaran S, Sivakumar K, Pavithran S, Rohitraj GR, Jayranganath M, Francis E (2021) Early multicenter experience of a new balloon expandable MyVal transcatheter heart valve in dysfunctional stenosed right ventricular outflow tract conduits. Ann Pediatr Cardiol 14(3):293–301. https://doi.org/10.4103/apc.apc_242_20
Rodríguez Ogando A, Ballesteros F, Martínez JLZ (2022) Pulmonary percutaneous valve implantation in large native right ventricular outflow tract with 32 mm Myval transcatheter heart valve. Catheter Cardiovasc Interv 99:E38–E42
Kenny D, Morgan GJ, Murphy M, AlAlwi K, Giugno L, Zablah J, Carminati M, Walsh K (2019) Use of 65 cm large caliber dryseal sheaths to facilitate delivery of the Edwards SAPIEN valve to dysfunctional right ventricular outflow tracts. Catheter Cardiovasc Interv 94(3):409–413. https://doi.org/10.1002/ccd.28409
Lourtet-Hascoët J, Valdeolmillos E, Houeijeh A, Bonnet E, Karsenty C, Sharma SR, Kempny A, Iung B, Gatzoulis MA, Fraisse A, Hascoët S (2023) Infective endocarditis after transcatheter pulmonary valve implantation in patients with congenital heart disease: distinctive features. Arch Cardiovasc Dis 116(3):159–166. https://doi.org/10.1016/j.acvd.2023.01.008
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MAN: First Author, and manuscript writing, AE: Data collection from Kosuyolu High Education Training and Research Hospital, BA: Data collection from Gazi Yaşargil Training and Research Hospital, AY: Data collection from Istanbul Medipol University Hospital, Istanbul, ZH: Data collection, supervised manuscript writing from Sidra medicine, AAS: Data collection and procedure performer from Prince Sultan Cardiac center, MAD: Data collection from Prince Sultan Cardiac center and also supervised in arranging data from all centers, YM: Data collection from Prince Sultan Cardiac center, ZAR: Data collection from Sidra Medicine, Qatar, YB: Procedure performer and supervised manuscript from Sidra medicine, HS: Procedure performer and supervised manuscript from Sidra medicine, OAT: Assisted in statistics and supervised manuscript, AMAO: assisted in procedure performance,TM: Senior Author and overall supervisor of the manuscript writing. All authors reviewed the manuscript.
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Al Nasef, M., Erdem, A., Aldudak, B. et al. Multicenter Experience for Early and Mid-Term Outcome of MyVal Transcatheter Pulmonary Valve Implantation. Pediatr Cardiol 45, 570–579 (2024). https://doi.org/10.1007/s00246-023-03398-1
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DOI: https://doi.org/10.1007/s00246-023-03398-1