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Consequences of increased neuromotor noise for reaching movements in persons with stroke

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Abstract

Understanding stroke-induced changes to the motor control of the more affected arm of people with stroke may lead to more effective rehabilitation interventions that improve function. Reaching movements of the more affected arm in persons with stroke are slow, segmented, and indirect. Such changes may be related to a reduced capacity to transmit motor commands in the presence of neuromotor noise. In tasks requiring both speed and accuracy, transmission capacity can be characterized by the linear relationship between movement time and task difficulty (Fitts’ law). This study quantified Fitts’ slope and intercept coefficients in stroke during reaching tasks and their relationship to kinematic measures of path accuracy (directness), trajectory corrections (segmentation), and planning strategy (skewness). We compared Fitts’ slope and intercept and kinematics among the more and the less affected arm of 20 persons with stroke and the nondominant arm of ten healthy persons. Slope and intercept were significantly increased in the more affected arm of the group with stroke and related to clinical measurements of motor impairment and tone. For both the more and the less affected arm of the group with stroke, increased slopes and intercepts were correlated to more indirect, segmented, and positively skewed movement. Our findings suggest that stroke results in greater neuromotor noise, which has consequences for both motor execution and planning. Individuals with stroke demonstrate substantially more deviation from straight-line paths than do controls, despite using more conservative strategies (i.e., leftward shift of velocity profile) and extensive feedback control (i.e., segmentation).

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Acknowledgements

The authors would like to thank the Canadian Institute of Health Research and Michael Smith Foundation of Health Research for salary support to J.J.E. and the Rick Hansen Neurotrauma Initiative for a studentship to P.H.M.

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Authors and Affiliations

  1. Department of Mechanical Engineering, University of BC, Vancouver, Canada

    Patrick H. McCrea

  2. School of Rehabilitation Sciences, University of BC, T325-2211 Wesbrook Mall, Vancouver, BC, V6T 2B5, Canada

    Janice J. Eng

  3. Rehabilitation Research Laboratory, G.F. Strong Rehabilitation Centre, Vancouver, BC, Canada

    Patrick H. McCrea & Janice J. Eng

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  1. Patrick H. McCrea
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  2. Janice J. Eng
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Correspondence to Janice J. Eng.

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McCrea, P.H., Eng, J.J. Consequences of increased neuromotor noise for reaching movements in persons with stroke. Exp Brain Res 162, 70–77 (2005). https://doi.org/10.1007/s00221-004-2106-8

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  • DOI: https://doi.org/10.1007/s00221-004-2106-8

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