Skip to main content

Advertisement

Log in

Adherence to nicotine replacement therapy versus quitting smoking among Chinese smokers: a preliminary investigation

  • Original Investigation
  • Published:
Psychopharmacology Aims and scope Submit manuscript

Abstract

Rationale

There are over 300 million Chinese smokers, but use of nicotine replacement therapy (NRT) is rare. On the other hand, data on the factors associated with quitting and adherence to NRT use are scarce in the East.

Objectives

To describe adherence and other predictors of quitting smoking at the 12-month follow-up amongst Chinese smokers in Hong Kong.

Methods

Chinese smokers (1186) who attended the Smoking Cessation Health Centre from August 2000 through January 2002 were studied. Trained counsellors provided individual counselling and carried out follow-up interviews. We used structured questionnaires at baseline and at 1, 3 and 12 months and an intention-to-treat approach for analysis.

Results

Among those who received NRT (1051/1186), the prevalence of adherence (self-reported NRT use for at least 4 weeks) was 16% (95% confidence interval 14–18%). The 7-day point prevalence quit rate at 12 months (not smoking any cigarette during the past 7 days at the 12 month follow-up) was 27% (95% CI, CI 24–29%). Stepwise logistic regression model showed that adherence to NRT use, a higher income, good perceived health and having more confidence in quitting were significant predictors of quitting. The quit rate in the adherent group (40%) was greater than that of the non-adherent group (25%) (P<0.001). Older age, male, higher education, experience of NRT use, perceiving quitting as more difficult and willingness to pay were significant predictors of adherence.

Conclusions

Clinically significant smoking cessation rates can be achieved among Chinese smokers in a clinic-based smoking cessation service. The NRT adherence was low and low adherence was associated with a lower quit rate. Trials of interventions to improve adherence and increase quit rates are needed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Alterman AI, Gariti P, Cook TG, Cnaan A (1999) Nicodermal patch adherence and its correlates. Drug Alcohol Depend 53:159–165

    Article  CAS  PubMed  Google Scholar 

  • Borrelli B, Hogan JW, Bock B, Pinto B, Roberts M, Marcus B (2002) Predictors of quitting and dropout among women in a clinic-based smoking cessation program. Psychol Addict Behav 16:22–27

    Article  PubMed  Google Scholar 

  • Census and Statistics Department, Hong Kong Government (1998) Special Topics Report No. 20. General Household Survey 1998. Government printer, Hong Kong. Available from http://www.info.gov.hk/censtatd/

  • Croghan IT, Offord KP, Evans RW et al (1997) Cost-effectiveness of treating nicotine dependence: the Mayo Clinic experience. Mayo Clin Proc 72:917–924

    CAS  PubMed  Google Scholar 

  • Curry SJ, Grothaus LC, McAfee T, Pabiniak C (1998) Use and cost effectiveness of smoking-cessation services under four insurance plans in a health maintenance organization. N Engl J Med 339:673–679

    Article  CAS  PubMed  Google Scholar 

  • Dale LC, Ebbert JO, Hays JT, Hurt RD (2000) Treatment of nicotine dependence. Mayo Clin Proc 75:1311–1316

    CAS  PubMed  Google Scholar 

  • Department of Health (2001) Statistics on smoking cessation services in England: April 2000–March 2001. Government Statistical Service, London

    Google Scholar 

  • Etter JF, Prokhorov AV, Perneger TV (2002) Gender differences in the psychological determinants of cigarette smoking. Addiction 97:733–743

    Article  PubMed  Google Scholar 

  • Fiore MC, Bailey WC, Cohen SJ et al (2000) Treating tobacco use and dependence. Clinical practice guideline. U.S. Department of Health and Human Services, Public Health Service, Rockville, MD. ISBN 1-58763-007-9

  • Fornai E, Desideri M, Pistelli F et al. (2001) Smoking reduction in smokers compliant to a smoking cessation trial with nicotine patch. Monaldi Arch Chest Dis 56:5–10

    CAS  PubMed  Google Scholar 

  • Gourlay SG, Benowitz NL, Forbes A, McNeil JJ (1997) Determinants of plasma concentrations of nicotine and cotinine during cigarette smoking and transdermal nicotine treatment. Eur J Clin Pharmacol 51:407–414

    Article  CAS  PubMed  Google Scholar 

  • Heatherton TF, Kozlowski LT, Frecker RC, Fagerstrom KO (1991) The Fagerstrom test for nicotine dependence: a revision of the Fagerstrom Tolerance Questionnaire. Br J Addict 86:1119–1127

    CAS  PubMed  Google Scholar 

  • Howells L, Wilson AC, Skinner TC, Newton R, Morris AD, Greene SA (2002) A randomized control trial of the effect of negotiated telephone support on glycaemic control in young people with type 1 diabetes. Diabet Med 19:643–648

    Article  CAS  PubMed  Google Scholar 

  • Hughes JR, Gulliver SB, Amori G, Mireault GC, Fenwick JF (1989) Effect of instructions and nicotine on smoking cessation, withdrawal symptoms and self-administration of nicotine gum. Psychopharmacology 99:486–491

    CAS  PubMed  Google Scholar 

  • Hughes JR, Keely JP, Niaura RS, Ossip-Klein DJ, Richmond RL, Swan GE (2003) Measures of abstinence in clinical trials: issues and recommendations. Nicotine Tob Res 5:13–25

    Article  PubMed  Google Scholar 

  • Hurt RD, Dale LC, Fredrickson PA et al (1994) Nicotine patch therapy for smoking cessation combined with physician advice and nurse follow-up. One-year outcome and percentage of nicotine replacement. JAMA 271:595–600

    Article  CAS  PubMed  Google Scholar 

  • Hurt RD, Croghan GA, Wolter TD et al. (2000) Does smoking reduction result in reduction of biomarkers associated with harm? A pilot study using a nicotine inhaler. Nicotine Tob Res 2:327–336

    CAS  PubMed  Google Scholar 

  • Imperial Cancer Research Fund General Practice Research Group (1993) Effectiveness of a nicotine patch in helping people stop smoking: results of a randomised trial in general practice. Br Med J 306:1304–1308

    Google Scholar 

  • Killen JD, Fortmann SP, Davis L, Strausberg L, Varady A (1999) Do heavy smokers benefit from higher dose nicotine patch therapy? Exp Clin Psychopharmacol 7:226–233

    Article  CAS  PubMed  Google Scholar 

  • Lam TH, Ho SY, Hedley AJ, Mak KH, Peto R (2001) Mortality and smoking in Hong Kong: case-control study of all adult deaths in 1998. BMJ 323:361–362

    Article  CAS  PubMed  Google Scholar 

  • McWhorter WP, Boyd GM, Mattson ME (1990) Predictors of quitting smoking: the NHANES I followup experience. J Clin Epidemiol 43:1399–1405

    Article  CAS  PubMed  Google Scholar 

  • Piette JD, Weinberger M, McPhee SJ, Mah CA, Kraemer FB, Crapo LM (2000) Do automated calls with nurse follow-up improve self-care and glycemic control among vulnerable patients with diabetes? Am J Med 108:20–27

    Article  CAS  PubMed  Google Scholar 

  • Prochaska JO, Goldstein MG (1991) Process of smoking cessation. Implications for clinicians. Clin Chest Med 12:727–735

    CAS  PubMed  Google Scholar 

  • Public Health Service (2000) Clinical practice guideline: treating tobacco use and dependence. US Department of Health and Human Services, USA. ISBN 1-58763-007-9

    Google Scholar 

  • Raw M, McNeill A, West R (1998) Smoking cessation guidelines for health professionals. A guide to effective smoking cessation interventions for the health care system. Thorax 53:S1–S19

    Google Scholar 

  • Razavi D, Vandecasteele H, Primo C, Bodo M, Debrier F et al. (1999) Maintaining abstinence from cigarette smoking: effectiveness of group counselling and factors predicting outcome. Eur J Cancer 35:1238–1247

    Article  CAS  PubMed  Google Scholar 

  • Russell MA, Stapleton JA, Feyerabend C et al. (1993) Targeting heavy smokers in general practice: randomised controlled trial of transdermal nicotine patches. BMJ 306:1308–1312

    CAS  PubMed  Google Scholar 

  • Ryff-de-Leche A, Engler H, Nutzi E, Berger M, Berger W (1992) Clinical application of two computerized diabetes management systems: comparison with the log-book method. Diabetes Res 19:97–105

    CAS  PubMed  Google Scholar 

  • Sabaté E (2003) Adherence to long-term therapies: evidence for action. World Health Organization, Geneva, Switzerland. ISBN 92-4-154599-2

  • Sachs DP, Sawe U, Leischow SJ (1993) Effectiveness of 16-hour transdermal nicotine patch in medical practice setting without intensive group counseling. Arch Intern Med 153:1881–1890

    Article  CAS  PubMed  Google Scholar 

  • Solomon IJ, Scharoun GM, Flynn BS, Secker-Walker RH, Sepinwall D (2000) Free nicotine patches plus proactive telephone peer support to help low-income women stop smoking. Prev Med 31:68–74

    Article  CAS  PubMed  Google Scholar 

  • Sonderskov J, Olsen J, Sabroe S, Meillier L, Overvad K (1997) Nicotine patches in smoking cessation: a randomized trial among over-the-counter customers in Denmark. Am J Epidemiol 145:309–318

    CAS  PubMed  Google Scholar 

  • Town GI, Fraser P, Graham S, McSweeney W, Brockway K, Kirk R (2000) Establishment of a smoking cessation programme in primary and secondary care in Canterbury. N Z Med J 113:117–119

    CAS  PubMed  Google Scholar 

  • Transdermal Nicotine Study Group (1991) Transdermal nicotine for smoking cessation. Six-month results from two multicenter controlled clinical trials. JAMA 266:3133–3138

    Google Scholar 

  • Velicer WF, Prochaska JO, Rossi JS, Snow MG (1992) Assessing outcome in smoking cessation studies. Psychol Bull 111:23–41

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgements

We thank Pharmacia Upjohn and Novartis for partially sponsoring the printing cost of the clinic pamphlets and providing some free NRT samples. The study was sponsored by the Hong Kong Council on Smoking and Health.

Conflicts of interest: T.H. Lam is vice chair of Hong Kong Council on Smoking and Health (COSH), A.J. Hedley was former chair of COSH and ASM Abdullah is the Director of the Hong Kong Smoking Cessation Health Centre. Smoking cessation services was supported in part by concessionary rates on NRT products.

Author information

Authors and Affiliations

Authors

Consortia

Corresponding author

Correspondence to Abu Saleh M. Abdullah.

Additional information

Professor A.J. Hedley (Chair Professor, Department of Community Medicine, The University of Hong Kong; Former Chairman, Hong Kong Council on Smoking and Health, COSH), Professor T.H. Lam (Head, Department of Community Medicine, The University of Hong Kong; Vice Chairman, COSH), Dr. A.S. M Abdullah, (Director, Hong Kong Smoking Cessation Health Centre; Research Assistant Professor, Department of Community Medicine, The University of Hong Kong), Dr. S.C. Chan (Head, Department of Nursing Studies, The University of Hong Kong), Mr. Marcus Yu and Dr. Raymond LM Ho (Former and current Executive Director, COSH), Dr. W.L. Lo (Council Member, COSH), Mr. Alfred Chan (Former Senior Project Manager, COSH), Professor Edith Lau, (Professor, Department of Community and Family Medicine, Chinese University of Hong Kong; Council Member, COSH), Dr. J.L. Tang (Associate Professor, Department of Community and Family Medicine, Chinese University of Hong Kong), Dr. S.Y. Chan (Associate Professor, Department of Community and Family Medicine, Chinese University of Hong Kong), Dr. H.C. Ma (Chief Executive, Ruttonjee Hospital), Dr. C.W. Lam (Head of Respiratory Medicine, Ruttonjee Hospital), Dr. Y.K. Lau (Head of Cardiology Division, Ruttonjee Hospital).

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lam, TH., Abdullah, A.S.M., Chan, S.S.C. et al. Adherence to nicotine replacement therapy versus quitting smoking among Chinese smokers: a preliminary investigation. Psychopharmacology 177, 400–408 (2005). https://doi.org/10.1007/s00213-004-1971-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00213-004-1971-y

Keywords

Navigation