Abstract
The study assessed the effect of offering a 4-week course of duloxetine therapy to 73 women awaiting a tension-free vaginal tape (TVT) operation. Twenty-seven women (37%) declined taking the drug, leaving 46 women (63%) willing to take drug therapy. Thirteen women were scheduled for a TVT with concurrent prolapse surgery, and 1 of these women decided that she no longer needed the surgery. Eight of the 33(24%) women scheduled for a TVT without concurrent prolapse surgery came off the waiting list. Nine women of the 33 women scheduled for a TVT without concurrent surgery (27%) found that the medication did not work sufficiently well. Sixteen of the 33 women (48%) discontinued medication due to side-effects. Women on a waiting list for surgery may be unwilling to take duloxetine therapy and less tolerant of side-effects.
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The authors would like to thank Dr. M. Brand (Research Co-ordinator), Maria Eaton (Urogynaecology Nurse Practitioner) for their help in producing this paper.
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Duckett, J.R.A., Aggarwal, I. & Patil, A. Duloxetine treatment for women awaiting continence surgery. Int Urogynecol J 17, 563–565 (2006). https://doi.org/10.1007/s00192-005-0063-9
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DOI: https://doi.org/10.1007/s00192-005-0063-9