Skip to main content
Log in

Quantitative measurement of heparin in comparison with conventional anticoagulation monitoring and the risk of thrombotic events in adults on extracorporeal membrane oxygenation

  • Letter
  • Published:
Intensive Care Medicine Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Vandiver JW, Vondracek TG (2012) Antifactor Xa levels vs activated partial thromboplastin time for monitoring unfractionated heparin. Pharmacotherapy 32(6):546–558

    Article  CAS  PubMed  Google Scholar 

  2. Atallah S, Liebl M, Fitousis K, Bostan F, Masud F (2014) Evaluation of the activated clotting time and activated partial thromboplastin time for the monitoring of heparin in adult extracorporeal membrane oxygenation patients. Perfusion 29(5):456–461

    Article  CAS  PubMed  Google Scholar 

  3. Liveris A, Bello RA, Friedmann P, Duffy MA, Manwani D, Killinger JS et al (2014) Anti-factor Xa assay is a superior correlate of heparin dose than activated partial thromboplastin time or activated clotting time in pediatric extracorporeal membrane oxygenation. Pediatr Crit Care Med 15(2):178–179

    Article  Google Scholar 

  4. Price EA, Jin J, Nguyen HM, Krishnan G, Bowen R, Zehnder JL (2013) Discordant aPTT and anti-Xa values and outcomes in hospitalized patients treated with intravenous unfractionated heparin. Ann Pharmacother 47(2):151–158

    Article  PubMed  Google Scholar 

  5. Irby K, Swearingen C, Byrnes J, Bryant J, Prodhan P, Fiser R (2014) Unfractionated heparin activity measured by anti-factor Xa levels is associated with the need for extracorporeal membrane oxygenation circuit/membrane oxygenator change: a retrospective pediatric study. Pediatr Crit Care Med 15(4):179–182

    Article  Google Scholar 

Download references

Acknowledgments

C.E.V. has grant support from the American Heart Association (11FTF7400032) and the National Institutes of Health (P20GM103652).

Conflicts of interest

C.E.V. has served as a consultant for Maquet Cardiovascular and Bayer. For the remaining authors none were declared.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Corey E. Ventetuolo.

Additional information

D. C. Chu and A. G. Abu-Samra shared first authorship.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Chu, D.C., Abu-Samra, A.G., Baird, G.L. et al. Quantitative measurement of heparin in comparison with conventional anticoagulation monitoring and the risk of thrombotic events in adults on extracorporeal membrane oxygenation. Intensive Care Med 41, 369–370 (2015). https://doi.org/10.1007/s00134-014-3574-3

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00134-014-3574-3

Keywords

Navigation