Abstract
Background
Monitoring the injured brain is an integral part of the management of severely brain injured patients in intensive care. Brain-specific monitoring techniques enable focused assessment of secondary insults to the brain and may help the intensivist in making appropriate interventions guided by the various monitoring techniques, thereby reducing secondary brain damage following acute brain injury.
Discussion
This review explores methods of monitoring the injured brain in an intensive care unit, including measurement of intracranial pressure and analysis of its waveform, and techniques of cerebral blood flow assessment, including transcranial Doppler ultrasonography, laser Doppler and thermal diffusion flowmetry.
Conclusions
Various modalities are available to monitor the intracranial pressure and assess cerebral blood flow in the injured brain in intensive care unit. Knowledge of advantages and limitations of the different techniques can improve outcome of patients with acute brain injury.
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Abbreviations
- ABP:
-
arterial blood pressure
- AMP:
-
amplitude of fundamental component of ICP waveform
- CBF:
-
cerebral blood flow
- CBV:
-
cerebral blood volume
- CO2 :
-
carbon dioxide
- CPP:
-
cerebral perfusion pressure
- CSF:
-
cerebrospinal fluid
- CT:
-
computerised tomography
- DID:
-
delayed ischaemic neurological deficit
- EDP:
-
effective downstream pressure
- FV:
-
flow velocity
- HDI:
-
haemodynamic impairment
- ICP:
-
intracranial pressure
- ICU:
-
intensive care unit
- LDF:
-
laser Doppler flowmetry
- MAP:
-
mean arterial pressure
- MCA:
-
middle cerebral artery
- MRI:
-
magnetic resonance imaging
- nCPP:
-
non-invasively determined cerebral perfusion pressure
- nICP:
-
non-invasive ICP measurement
- PET:
-
positron emission tomography
- PI:
-
pulsatility index
- PRx:
-
pressure reactivity index
- RI:
-
resistance index
- RAP:
-
correlation of amplitude and pressure of ICP waveform
- SAH:
-
subarachnoid haemorrhage
- TBI:
-
traumatic brain injury
- TCD:
-
transcranial Doppler
- TD:
-
thermal diffusion
- THRT:
-
transient hyperaemic response test
- US:
-
ultrasound
- ZFP:
-
zero flow pressure
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Part II of this article is available at: http://dx.doi.org/10.1007/s00134-007-0660-9.
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Bhatia, A., Gupta, A.K. Neuromonitoring in the intensive care unit. I. Intracranial pressure and cerebral blood flow monitoring. Intensive Care Med 33, 1263–1271 (2007). https://doi.org/10.1007/s00134-007-0678-z
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DOI: https://doi.org/10.1007/s00134-007-0678-z