Abstract
Effects of benzoic acid (BA) on physicochemical properties and ecotoxicities of CuO nanoparticles (CuONPs) in model aqueous media were studied. The CuONPs had larger hydrodynamic sizes and higher surface zeta potentials during 96 h of settling in the presence of BA than when the BA were not present. BA interaction with CuONPs is shown to promote dissolved Cu release from CuONPs in a dose-dependent manner. The contribution of free Cu2+-ions to growth inhibition toxicity of the CuONP suspensions at a toxicologically relevant concentration for the green alga Scenedesmus obliquus was around 22 %, indicating that dissolved fraction was not the major source of toxicity of CuONPs. The toxicity of CuONPs increased as the BA concentration increased. BA significantly altered total antioxidant capacity of CuONPs-exposed algal cells. The mechanism of the BA effect on the CuONPs toxicity may be mainly associated with degree of agglomeration, dissolved Cu, and particle-induced oxidative stress.
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Acknowledgments
We gratefully acknowledge the National Natural Science Foundation of China (21407080) and the Foundation Research Project of Jiangsu Province (BK20140987 and BK20150891). We also thank the Startup Foundation for Introducing Talent (2014r020 and 2015r011) and the open fund by Laboratory/Equipment Management Office (15KF052 and 15KF053) of Nanjing University of Information Science and Technology.
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Zhuang Wang and Hao Fang have contributed equally to this work.
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Wang, Z., Fang, H. & Wang, S. Benzoic Acid Interactions Affect Aquatic Properties and Toxicity of Copper Oxide Nanoparticles. Bull Environ Contam Toxicol 97, 159–165 (2016). https://doi.org/10.1007/s00128-016-1804-9
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DOI: https://doi.org/10.1007/s00128-016-1804-9