Skip to main content
SpringerLink
Log in

Standards und Perspektiven in der Diagnostik und Therapie des Harnblasenkarzinoms

  • Leitthema
  • Published:
Der Urologe Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Abb. 1
Abb. 2
Abb. 3
Abb. 4

Literatur

  1. Advanced bladder cancer (ABC) Meta-analysis Collaboration (2005) Adjuvant chemotherapy in invasive bladder cancer: A systematic review and meta-analysis of individual patient data. Eur Urol 48: 189–201

    Article  PubMed  Google Scholar 

  2. Clark PE, Stein JP, Groshen SG et al. (2005) Radical cystectomy in the elderly: comparison of clincal outcomes between younger and older patients. Cancer 104(1): 36–43

    Article  PubMed  Google Scholar 

  3. Coppin CM, Gospodarowicz MK, James K et al. (1996) Improved local control of invasive bladder cancer by concurrent cisplatin and preoperative or definitive radiation. The National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 14: 2901–2907

    PubMed  Google Scholar 

  4. Daniltchenko DI, Riedl CR, Sachs MD et al. (2005) Long-term benefit of 5-aminolevulinic acid fluorescence assisted transurethral resection of superficial bladder cancer: 5-year results of a prospective randomized study. J Urol 174(6): 2129–2133

    Article  PubMed  Google Scholar 

  5. Dunst J, Sauer R, Schrott KM et al. (1994) Organ-sparing treatment of advanced bladder cancer: a 10-year experience. Intern J Radiat Oncol Biol Phys 30: 261–266

    Google Scholar 

  6. Eble JN, Sauter G, Epstein JI, Sesterhenn IA (eds) (2004) World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. IARC Press, Lyon

  7. Filbeck T, Pichlmeier U, Knüchel R et al. (2003) Reducing the risk of superficial bladder cancer recurrence with 5-aminolevulinic acid-induced fluorescence diagnosis. Results of a 5-year study Urologe A 42: 1366–373

    Google Scholar 

  8. Fleischmann A, Thalmann GN, Studer UE et al. (2005) Extracapsular extension of pelvic lymph node metastases from urothelial carcinoma of the bladder is an independent prognostic factor. J Clin Oncol 23: 2358–2365

    Article  PubMed  Google Scholar 

  9. Ghoneim MA, el-Mekresh MM, Ashamallah A et al. (1997) Radical cystectomy for carcinoma of the bladder: critical evaluation of the results in 1,026 cases. J Urol 158: 393–399

    Article  PubMed  Google Scholar 

  10. Gschwend JE, Volkmer BG, Hautmann RE (2004) Radical cystectomy for bladder cancer in the neobladder era – progression and survival in 674 consecutive patients. J Urol [Suppl] 80

  11. Habuchi T, Marberger M, Droller MJ et al. (2005) Prognostic markers for bladder cancer: International Consensus Panel on bladder tumor markers. Urology 66 [6 Suppl 1]: 64–74

  12. Hautmann RE, Paiss T (1998) Does the option of the ileal neobladder stimulate patient and physician decision toward earlier cystectomy? J Urol 159: 1845

    Article  PubMed  Google Scholar 

  13. Housset M, Maulard C, Chretien Y et al. (1993) Combined radiation and chemotherapy for invasive transitional-cell carcinoma of the bladder: a prospective study. J Clin Oncol 11: 2150–2157

    PubMed  Google Scholar 

  14. Housset M, Dufour B, Maulard-Durdux C et al. (1997) Concomitant fluorouracil (5-FU)-cisplatin (CDDP) and bifractionated split course radiation therapy (BSCRT) for invasive bladder cancer. Proc Am Soc Clin Oncol 16: 319

    Google Scholar 

  15. Kessler TM, Burkhard FC, Perimenis P et al. (2004) Attempted nerve sparing surgery and age have a significant effect on urinary continence and erectile function after radical cystoprostatectomy and ileal orthotopic bladder substitution. J Urol 172(4 Pt 1): 1323–1327

    Article  PubMed  Google Scholar 

  16. Lehmann J, Retz M, Wiemers C et al. (2005) Adjuvant cisplatin plus methotrexate versus methotrexate, vinblastine, epirubicine, and cisplatin in locally advanced bladder cancer: results of a randomized, multicenter, phase III trial (AUO-AB 05/95). J Clin Oncol 23: 4963–4974

    Article  PubMed  Google Scholar 

  17. Lehmann J, Gerber M, Franzaring L et al. (2006) Complete longterm survival data from a trial on adjuvant chemotherapy versus control after radical cysstectomy for locally advanced bladder cancer. BJU Int (im Druck)

  18. Leissner J, Hohenfellner R, Thuroff JW et al. (2000) Lymphadenectomy in patients with transitional cell carcinoma of the urinary bladder; significance for staging and prognosis. BJU Int 85: 817–823

    Article  PubMed  Google Scholar 

  19. Lerner SP, Skinner DG, Hopwood B et al. (1993) The rationale for en bloc pelvic lymph node dissection for bladder cancer patients with nodal metastases: long-term results. J Urol 149: 758–64

    PubMed  Google Scholar 

  20. Lodde M, Palermo S, Comploj E et al. (2005) Four years experience in bladder preserving management for muscle invasive bladder cancer. Eur Urol 47(6): 773–778

    Article  PubMed  Google Scholar 

  21. Madersbacher S, Hochreiter W, Burkhard F et al. (2003) Radical cystectomy for bladder cancer today – a homogeneous series without neoadjuvant therapy. J Clin Oncol 21(4): 690–696

    Article  PubMed  Google Scholar 

  22. Mills RD, Turner WH, Studer UE et al. (2001) Pelvic lymph node metastases from bladder cancer: outcome in 83 patients after radical cystectomy and pelvic lymphadenectomy. J Urol 166: 19–23

    Article  PubMed  Google Scholar 

  23. Mostofi FK, Davis CJ, Sesterhenn IA (1999) World Health Organizsation International Histological classification of tumours. Histological typing of urinary bladder tumours, 2nd edn. Springer, Berlin Heidelberg New York

  24. Poulsen AL, Horn T, Steven K (1998) Radical cystectomy: extending the limits of pelvic lymph node dissection improves survival for patients with bladder cancer confined to the bladder wall. J Urol 160: 2015–2019

    Article  PubMed  Google Scholar 

  25. Retz M, Lehmann J, Szysnik C et al. (2004) Detection of occult tumor cells in lymph nodes from bladder cancer patients by MUC7 nested RT-PCR. Eur Urol 45: 314–419

    Article  PubMed  Google Scholar 

  26. Rodel C, Weiss C, Sauer R (2005) Organ preservation by combined modality treatment in bladder cancer: the European perspective. Semin Radiat Oncol 15: 28–35

    Article  PubMed  Google Scholar 

  27. Rödel C, Grabenbauer GG, Kuhn R et al. (2002) Combined-modality treatment and selective organ preservation in invasive bladder cancer: long-term results. J Clin Oncol 20: 3061–3071

    Article  PubMed  Google Scholar 

  28. Sauer R, Birkenhake S, Kuhn R et al. (1998) Efficacy of radiochemotherapy with platin derivatives compared to radiotherapy alone in organ-sparing treatment of bladder cancer. Intern J Radiat Oncol Biol Phys 40: 121–127

    Article  Google Scholar 

  29. Sanchez-Ortiz RF, Huang WC, Mick R et al. (2003) An interval longer than 12 weeks between the diagnosis of muscle invasion and cystectomy is associated with worse outcome in bladder carcinoma. J Urol 169(1): 110–115

    Article  PubMed  Google Scholar 

  30. Shipley WU, Kaufman DS, Zehr E et al. (2002) Selective bladder preservation by combined modality protocol treatment: long-term outcomes of 190 patients with invasive bladder cancer. Urology 60: 62–68

    Article  PubMed  Google Scholar 

  31. Skinner DG (1982) Management of invasive bladder cancer: a meticulous pelvic node dissection can make a difference. J Urol 128: 34–36

    PubMed  Google Scholar 

  32. Stein JP, Lieskovsky G, Cote R et al. (2001) Radical cystectomy in the treatment of invasive bladder cancer: long-term results in 1.054 patients. J Clin Oncol 19(3): 666–675

    PubMed  Google Scholar 

  33. Stein JP, Cai J, Groshen S, Skinner DG (2003) Risk factors for patients with pelvic lymph node metastases following radical cystectomy with en bloc pelvic lymphadenectomy: concept of lymph node density. J Urol 170: 35–41

    Article  PubMed  Google Scholar 

  34. Stoehr R, Knuechel R, Boecker J et al. (2002) Histologic-genetic mapping by allele-specific PCR reveals intraurothelial spread of p53 mutant tumor clones. Lab Invest 82: 1553–1561

    PubMed  Google Scholar 

  35. Stöckle M, Meyenburg W, Wellek S et al. (1995) Adjuvant polychemotherapy of nonorgan-confined bladder cancer after radical cystectomy revisited – long-term results of a controlled prospective study and further clinical experience. J Urol 153: 47–52

    Article  PubMed  Google Scholar 

  36. Stöckle M, Lehmann J (2005) Therapie und Prognose des lymphogen metastasierten Urothelkarzinoms – Stellenwert der Lymphknotenchirugie und der perioperativen systemischen Chemotherapie. In: Lehmann J, Retz M, Stöckle M (Hrsg) Blasenkarzinom – Neue Perspektiven in Diagnostik und Therapie. Springer, Berlin Heidelberg New York

  37. Sylvester RJ, Oosterlinck W, van der Meijden AP (2004) A single immediate postoperative instillation of chemotherapy decreases the risk of recurrence in patients with stage Ta T1 bladder cancer: a meta-analysis of published results of randomized clinical trials. J Urol 171(6 Pt 1): 2186

    Article  PubMed  Google Scholar 

  38. Sylvester RJ, van der Meijden AP, Oosterlinck W et al. (2006) Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables: a combined analysis of 2596 patients from seven EORTC trials. Eur Urol 49(3): 466–465

    Article  PubMed  Google Scholar 

  39. Vallancien G, Abou El Fettouh H, Cathelineau X et al. (2002) Cystectomy with prostate sparing for bladder cancer in 100 patients: 10-year experience. J Urol 168(6): 2413–2317

    Article  PubMed  Google Scholar 

  40. van der Meijden AP, Sylvester R, Oosterlinck W et al. (2005) EAU guidelines on the diagnosis and treatment of urothelial carcinoma in situ. Eur Urol 48(3): 363–371

    PubMed  Google Scholar 

  41. van Rhijn BW, van der Poel HG, van der Kwast TH (2005) Urine markers for bladder cancer surveillance: a systematic review. Eur Urol 47(6): 736–748

    Article  PubMed  Google Scholar 

  42. Vieweg J, Gschwend JE, Herr HW et al. (1999) Pelvic lymph node dissection can be curative in patients with node positive bladder cancer. J Urol 161: 449–454

    Article  PubMed  Google Scholar 

  43. Zaak D, Hungerhuber E, Schneede P et al. (2002) Role of 5-aminolevulinic acid in the detection of urothelial premalignant lesions. Cancer 95(6): 1234–1238

    Article  PubMed  Google Scholar 

  44. Zaak D, Karl A, Knüchel R et al. (2005) Diagnosis of urothelial carcinoma of the bladder using fluorescence endoscopy. BJU Int 96(2): 217–222

    Article  PubMed  Google Scholar 

Download references

Interessenkonflikt

Es besteht kein Interessenkonflikt. Der korrespondierende Autor versichert, dass keine Verbindungen mit einer Firma, deren Produkt in dem Artikel genannt ist, oder einer Firma, die ein Konkurrenzprodukt vertreibt, bestehen. Die Präsentation des Themas ist unabhängig und die Darstellung der Inhalte produktneutral.

Author information

Authors and Affiliations

  1. Urologische Klinik und Poliklinik, Klinikum der Ludwig-Maximilians-Universität , Marchioninistraße 15, 81377, München

    C. Stief & D. Zaak

  2. Klinik für Urologie und Kinderurologie, Universitätsklinikum des Saarlandes, Homburg/Saar

    M. Stöckle

  3. Urologische Universitätsklinik, Inselspital, Bern, Schweiz

    U. Studer

  4. Institut für Pathologie, Universitätsklinikum, RWTH , Aachen

    R. Knuechel

  5. Klinik für Strahlentherapie, Universität Erlangen

    C. Rödel & R. Sauer

  6. Urologische Klinik und Poliklinik, Universitätsklinikum Essen

    H. Rubben

Authors
  1. C. Stief
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. D. Zaak
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. Stöckle
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. U. Studer
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. R. Knuechel
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. C. Rödel
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. R. Sauer
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. H. Rubben
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to C. Stief.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Stief, C., Zaak, D., Stöckle, M. et al. Standards und Perspektiven in der Diagnostik und Therapie des Harnblasenkarzinoms. Urologe 45 (Suppl 4), 90–96 (2006). https://doi.org/10.1007/s00120-006-1134-3

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00120-006-1134-3

Search

Navigation