Zusammenfassung
Dieser Artikel gibt eine Übersicht zur Komorbidität von Typ-1-Diabetes und Essstörungen im Kindes- und Jugendalter. Neben der Darstellung epidemiologischer Daten und von Untersuchungsansätzen werden theoretische Annahmen zum Zusammentreffen beider Krankheitsbilder bzw. deren mögliche Entstehungsgrundlagen zusammengeführt und diskutiert. Darüber hinaus werden somatische Komplikationen und weitere in Betracht kommende Langzeitfolgen aufgelistet. Schlussfolgernd ergibt sich die Forderung nach einer erhöhten Anstrengung interdisziplinärer Bemühungen um die genannte Patientengruppe, welche mit einem deutlich erhöhten Mortalitätsrisiko behaftet ist.
Abstract
This paper gives an overview of concurrent type 1 diabetes mellitus and eating disorders during childhood and adolescence. In addition to the presentation of epidemiological data and study designs, theoretical assumptions on the concurrence of both diseases and on the causality of both are summarized and discussed. In addition, somatic complications are listed and long-term sequelae are considered. The authors identify a need for further research and interdisciplinary management efforts on behalf of this patient group, which is characterized by an elevated risk of mortality.
Literatur
American Psychiatric Association (1994) Diagnostic and statistical manual of mental disorders (DSM-IV), 4th edn. American Psychiatric Association, Washington
Bahrke U, Bandemer-Greulich U, Fikentscher E et al. (2006) Erfassung essgestörten Verhaltens bei Patienten mit Diabetes mellitus mit Hilfe eines Fragebogens (Diab-Ess). Diabetologie 1: 46–53
Birmingham CL, Su J, Hlynski JA et al. (2005) The mortality rate from anorexia nervosa. Int J Eating Disord 38: 143–148
Blanz BJ, Rensch-Riemann BS, Fritz-Sigmund DI et al. (1993) IDDM as a risk factor for adolescent psychiatric disorders. Diabetes Care 16: 1579–1587
Celi F, Bini V, Papi F et al. (2005) Circulating acyclated and total ghrelin and galanin in children with insulin-treated type 1 diabetes: relationship to insulin therapy, metabolic control and pubertal development. Clin Endocrinol 63: 139–145
Dilling H, Mombour W, Schmidt MH (Hrsg) (1991) Internationale Klassifikation psychischer Störungen. ICD-10, Kapitel V. Huber, Bern Stuttgart Toronto
Glastras SJ, Craig ME, Verge CF et al. (2005) The role of autoimmunity at diagnosis of type 1 diabetes in the development of thyroid and celiac disease and microvaskular complications. Diabetes Care 28: 2170–2175
Goodwin RD, Hoven CW, Spitzer RL (2003) Diabetes and eating disorders in primary care. Int J Eat Disord 33: 85–91
Grylli V, Hafferl-Gattermayer A, Schober E et al. (2004) Prevalence and clinical manifestations of eating disorders in Austrian adolescents with type-1 diabetes. Wien Klin Wochenschr 116: 230–234
Grylli V, Wagner G, Hafferl-Gattermayer A et al. (2005) Disturbed eating attitudes, coping styles, and subjective quality of life in adolescents with type 1 diabetes. J Psychosom Res 59: 65–72
Hebebrand J, Geller F, Dempfle A et al. (2004) Binge-eating episodes are not characteristic of carriers of melanocortin-4 receptor gene mutations. Mol Psychiatry 9: 796–800
Herpertz S, Wagener R, Albus C et al. (1998) Diabetes mellitus and eating disorders: a multicenter study on the comorbidity of the two diseases. J Psychosom Res 44: 503–515
Hoek HW, Van Hoeken D (2003) Review of the prevalence and incidence of eating disorders. Int J Eat Disord 34: 383–396
Jones JM, Lawson ML, Danemann D et al. (2000) Eating disorders in adolescent females with and without diabetes type 1 diabetes: cross sectional study. BMJ 320: 1563–1566
Kelly SD, Howe CJ, Hendler JP et al. (2005) Disordered eating behaviors in youth with type 1 diabetes. Diabetes Educ 34: 572–582
Kovacs M, Goldston D, Obrosky DS et al. (1997) Psychiatric disorders in youths with IDDM: rates and risk factors. Diabetes Care 20: 36–44
Kovacs M, Obrosky DS, Goldston D et al. (1997) Major depressive disorder in youths with IDDM. Diabetes Care 20: 45–51
Mannuci E, Rotella F, Ricca V et al. (2005) Eating disorders in patients with type 1 diabetes: a meta-analysis. J Endocrinol Invest 28: 417–419
McCarthy S, Mottagui-Tabar S, Mizuno Y et al. (2005) Complex HTR2C linkage disequilibrium and promoter associations with body mass index and serum leptin. Hum Genet 117: 545–557
Nielsen S, Emborg C, Molbak A-G (2002) Mortality in concurrent type 1 diabetes and anorexia nervosa. Diabetes Care 25: 309–312
Peveler RC, Bryden K, Neil HAW et al. (2005) The Relationship of disordered eating habits and attitudes to clinical outcomes in young adult females with type 1 diabetes. Diabetes Care 28: 84–88
Polivy J, Herman CP (1989) Dieting and bingeing: a causal analysis. Am Psychol 40: 193–201
Polonsky WH, Anderson BJ, Lohrer PA et al. (1994) Insulin omission in women with IDDM. Diabetes Care 17: 1178–1185
Riihimaa H, Knip M, Ruokonen A et al. (2002) Lack of physiological suppression of circulating IGFBP-1 in puberty in patients with insulin-dependent diabetes mellitus. Eur J Endocrinol 147: 235–241
Rubin RR, Peyrot M (1999) Persistence of depressive symptoms in diabetes. Diabetes Care 22: 448–452
Rubin RR, Peyrot M (2001) Psychological issues and treatments for people with diabetes. J Clin Psychol 57: 467–478
Scarpace PJ, Matheny M, Tümer N et al. (2005) Leptin resistance exacerbates diet-induced obesity and is associated with diminished maximal leptin signalling capacity in rats. Diabetologica 48: 1075–1083
Stachow R, Wolf J, Kromeyer-Hauschild K et al. (2003) Übergewicht und Adipositas bei Kindern und Jugendlichen mit Diabetes mellitus Typ 1. Monatsschr Kinderheilk 151:194–201
Stice E, Agras WS (1999) Subtyping bulimic women along dietary restraint and negative affect dimension. J Consult Clin Psychol 67: 460–469
Svensson M, Engström I, Aman J (2003) Higher drive for thinness in adolescent males with insulin-dependent diabetes mellitus compared with healthy controls. Acta Paediatr 92: 114–117
Interessenkonflikt
Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Schulze, U., Holl, R. & Goldbeck, L. Essstörungen und Typ-1-Diabetes im Kindes- und Jugendalter. Monatsschr Kinderheilkd 156, 887–892 (2008). https://doi.org/10.1007/s00112-007-1615-5
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00112-007-1615-5