Skip to main content
SpringerLink
Log in

Interaktion von Statinen mit Clopidogrel

  • Leserfragen
  • Published:
Der Internist Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Abb. 1

Literatur

  1. Bhatt DL, Bertrand ME, Berger PB et al. (2002) Meta-Analysis of randomized and registry comparisons of ticlopidine with clopidogrel after stenting. J Am Coll Cardiol 39: 9-14

    Article  CAS  PubMed  Google Scholar 

  2. Clarke TA, Waskell LA (2003) The metabolism of clopidogrel is catalyzed by human cytochrome p 450 3A and is inhibited by atorvastatin. Drug Metabol Dispos 31: 53–59

    Article  CAS  Google Scholar 

  3. Lau WC, Waskell LA, Watkins PB et al. (2003) Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation. A new drug-drug interaction. Circulation 107: 32–37

    Article  CAS  PubMed  Google Scholar 

  4. Mueller I, Besta F, Schulz C, Li Z, Massberg S, Gawaz M (2003) Effects of statins on platelet inhibition by a high loading dose of clopidogrel. Circulation 108: 2195–2197

    Article  CAS  PubMed  Google Scholar 

  5. Mueller C, Roskamm H, Neumann FJ, Hunziker P, Marsch S, Perruchoud A, Buettner HJ (2003) A randomized comparison of clopidogrel and aspirin versus ticlopidine and aspirin after the placement of coronary artery stents. J Am Coll Cardiol 41: 969–973

    Article  CAS  PubMed  Google Scholar 

  6. Saw J, Steinhubl SR, Berger PB, Kereiakes DJ, Serebruany VL, Brennan D, Topol EJ for the CREDO Investigators (2003) Lack of adverse clopidogrel-atorvastatin clinical interaction from secondary analysis of a randomized, placebo-controlled clopidogrel trial. Circulation 108: 921–924

    Article  CAS  PubMed  Google Scholar 

  7. Schafer AI (2003) Genetic and acquired determinants of individual variability of response to antiplatelet drugs. Circulation 108: 910–911

    Article  PubMed  Google Scholar 

  8. Serebruany VL, Malinin AI, Kallahan KP (2001) Statins do not affect platelet inhibition with clopidogrel during coronary stenting. Atherosclerosis 239: 259–261

    Google Scholar 

  9. Serebruany VL, Midei MG, Malinin AI et al. (2003) Atorvastatin does not affect the antiplatelet properties of clopidogrel in patients undergoing coronary stenting in randomized data from the interaction of atorvastatin and clopidogrel (INTERACTION) trial. J Am Coll Cardiol 41: 302A

    Article  Google Scholar 

  10. Serebruany VL, Steinhuble SR, Hennekens CH (2003) Are antiplatelet effects of clopidogrel inhibited by atorvastatin? Circulation 107: 1568–1569

    Article  PubMed  Google Scholar 

  11. Wienbergen H, Gitt AK, Schiele R et al. for the MITRA-PLUS study group (2003) Comparison of clinical benefits of clopidogrel therapy in patients with acute coronary syndromes taking atorvastatin versus other statin therapies. Am J Cardiol 92: 285–288

    Article  CAS  PubMed  Google Scholar 

Download references

Interessenkonflikt:

Der korrespondierende Autor versichert, dass keine Verbindungen mit einer Firma, deren Produkt in dem Artikel genannt ist, oder einer Firma, die ein Konkurrenzprodukt vertreibt, bestehen.

Author information

Authors and Affiliations

  1. I. Medizinische Klinik, Klinikum Augsburg

    W. von Scheidt

  2. I. Medizinische Klinik, Klinikum Augsburg, Stenglinstraße 2, 86156, Augsburg

    W. von Scheidt

Authors
  1. W. von Scheidt
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to W. von Scheidt.

Rights and permissions

Reprints and permissions

About this article

Cite this article

von Scheidt, W. Interaktion von Statinen mit Clopidogrel. Internist 45, 363–365 (2004). https://doi.org/10.1007/s00108-004-1147-1

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00108-004-1147-1

Search

Navigation