Skip to main content
Log in

Lymphknotenschwellung in der Leiste

Ungewöhnliche Ursache bei einer 65-jährigen Patientin

  • Kasuistiken
  • Published:
Der Internist Aims and scope Submit manuscript

Zusammenfassung

Eine 65 Jahre alte Patientin wurde mit unspezifischen Symptomen unter dem Verdacht auf ein malignes Lymphom in der rechten Leiste stationär aufgenommen. Histologisch stellte sich jedoch ein follikulärer dendritischer Retikulumzelltumor (FDC-Tumor) heraus. Da es für diese Art von Tumoren keine etablierte Therapie gibt, jedoch auch durchaus sehr aggressive Verläufe berichtet wurden, entschlossen wir uns nach der chirurgischen Tumorresektion zu einer zusätzlichen kombinierten Radio-Chemotherapie. Trotz dieser Maßnahmen kam es 16 Monate nach der Erstdiagnose zu einem neu aufgetretenen Prozess in der Lunge, welcher sich als Filia des follikulären dendritischen Retikulumzelltumors herausstellte. Dieser wurde reseziert. Nach wie vor ist unklar, welches die optimale Therapie für diese Tumoren ist.

Abstract

A 65 year old female patient was admitted to our hospital with unspecific symptoms and a lump in the right groin which raised suspicion of a malignant lymphoma. Histologically a follicular dendritic reticular cell tumor was found. Because there are aggressive forms of this tumor and no established standard therapy, we decided to treat her with surgery followed by a combined radio- and chemotherapy. Despite this treatment 16 months after the first diagnosis a relapse occurred with a metastasis of the follicular dendritic cell tumor in the lung. The metastasis was resected surgically. The optimal management of this kind of tumor is not known.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1
Abb. 2

Literatur

  1. Biddle D, Ro JY, Yoon GS (2002) Extranodal follicular dendritic cell sarcoma of the head and neck region: three new cases with a review of the literature. Mod Pathol 15: 50–58

    PubMed  Google Scholar 

  2. Chan JK, Fletcher DM, Nayler J (1997) Follicular dendritic cell sarcoma. clinicopathologic analysis of 17 cases suggesting a malignant potential higher than currently recognized. Cancer 79: 294–313

    Article  CAS  PubMed  Google Scholar 

  3. Choi P, To KF, Lai FM (2000) Follicular dendritic cell sarcoma of the neck. Report of two cases complicated by pulmonary metastases. Cancer 89: 664–672

    Article  CAS  PubMed  Google Scholar 

  4. Han JH, Kim SH, Lee YC, Noh SH, Yang WI (2000) Follicular dendritic cell sarcoma presenting as a submucosal tumor of the stomach. Arch Pathol Lab Med 124 1693–96

    Google Scholar 

  5. Lawrence W, Donegan W, Natarjan N (1987) Adult soft tissue sarcomas: A pattern of survey of the American College of Surgeons. Ann Surg 205: 349–359

    PubMed  Google Scholar 

  6. Monda L, Rosai J, Warnke R (1986) A primary lymph node malignancy with features suggestive of a dendritic reticulum cell differentiation. A report of four cases. Am J Pathol 122: 562–72

    CAS  PubMed  Google Scholar 

  7. Perez-Ordonez B, Erlandson RA, Rosai J (1996) Follicular dendritic cell tumor: report of 13 additional cases of a distinctive entity. Am J Surg Pathol 20: 944–55

    Article  CAS  PubMed  Google Scholar 

  8. Perez-Ordonez B, Rosai J (1998) Follicular dendritic cell tumor: review of the entity. Semin Diagn Pathol 5: 144–54

    Google Scholar 

  9. Pileri SA, Banks P, Campo E, Chan JK, Desol G, Favera RD, GroganTM (2002) Tumors of the histiocytes and accessory dendritic cells: an immunohistochemical approach to classification from the International Lymphoma Study Group based on 61 cases. Histopathology 41: 1-29

    Article  CAS  Google Scholar 

  10. Vargas H, Mouzakes J, Purdy SS, Parnes SM (2002) Follicular dendritic cell tumor: an aggressive head and neck tumor. Am J Otolaryngol 23: 93–98

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to C. Mozek.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mozek, C., Novotny, J., Dührsen, U. et al. Lymphknotenschwellung in der Leiste. Internist 45, 90–92 (2004). https://doi.org/10.1007/s00108-003-1101-7

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00108-003-1101-7

Schlüsselwörter

Keywords

Navigation