Zusammenfassung
Handekzeme zählen zu den häufigsten Hauterkrankungen, wobei sie jedoch keine homogene Krankheitsentität darstellen. Der Schweregrad kann von sehr leichten Ausprägungen bis zu schweren chronischen Fällen reichen, die eine lang dauernde Krankschreibung erforderlich machen können und teilweise therapierefraktär sind. Chronische Handekzeme sind mit hohen gesundheitsökonomischen Kosten und mit einem erheblichen Verlust an Lebensqualität verbunden. Obwohl es zahlreiche Therapieoptionen gibt, ist die Therapie des chronischen Handekzems oft schwierig und unbefriedigend. Es fehlen randomisierte klinisch kontrollierte Studien hoher Qualität zur Wirksamkeit selbst etablierter Therapieoptionen.
Abstract
Hand eczema (HE) is one of the most frequent skin diseases, although it is not a homogenous entity. The degree of severity can range from mild manifestations to severe chronic cases which are refractory to therapy and tend to disable patients. Chronic HE is a high social and economic impact and often leads to a loss in quality of life. Although there are many options, the therapy of chronic HE is difficult and often unsuccessful. Randomized controlled clinical trials demonstrating the efficacy of therapeutic options, including established ones, are lacking.
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Diepgen, T. Chronisches Handekzem. Hautarzt 59, 683–689 (2008). https://doi.org/10.1007/s00105-008-1560-9
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DOI: https://doi.org/10.1007/s00105-008-1560-9