Skip to main content
Log in

Eosinophile Ösophagitis

Signifikanz von Routinebiopsien des Ösophagus bei unklarer Dysphagie

Eosinophilic oesophagitis

Significance of routine oesophageal biopsies for dysphagia of unknown aetiology

  • Kasuistiken
  • Published:
Der Chirurg Aims and scope Submit manuscript

Zusammenfassung

Die eosinophile Ösophagitis (EÖ), ein primär internistisches Krankheitsbild, sollte dem Chirurgen und Endoskopiker als Differenzialdiagnose der Dysphagie geläufig sein. Wir präsentieren einen chronischen Fall einer EÖ. Wie so häufig, zeigen sich makroskopische Hinweise auf die ursächliche Erkrankung. Die Diagnose wird letztendlich durch den histologischen Befund einer makroskopisch unauffälligen Mukosa des Ösophagus gestellt, welche sich bei 10% der EÖ findet. Eine Stufenbiopsie ist zur Diagnosesicherung notwendig. Ein kurzer Überblick über Therapie und Verlauf sowie ein Review der Literatur werden gegeben.

Abstract

Eosinophilic oesophagitis (EO), primarily a gastro-enterological disease, should be known to the surgeon and endoscopist as a differential diagnosis of dysphagia. We present a chronic and recurrent case of EO. As frequently seen, macroscopic findings are indicative of the causal illness. The diagnosis is finally made by the histological findings of a macroscopically inconspicuous mucosa of the esophagus, which is found in 10% of cases with EO. Random biopsies are necessary for the diagnosis. A short overview of therapy and course and a review of the literature are given.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Abb. 1
Abb. 2
Abb. 3

Literatur

  1. Attwood SE, Smyrk TC, DeMeester et al (1993) Esophageal eosinophilia with dysphagia, a distinct clinicopathologic syndrome. Dig Dis Sci 38:109–116

    Article  CAS  PubMed  Google Scholar 

  2. Straumann A, Spichtin HP, Bernoulli R et al (1994) Idiopathic eosinophilic esophagitis: a frequently overlooked disease with typical clinical aspects and discrete endoscopic findings. Schweiz Med Wochenschr 124:1419–1429

    CAS  PubMed  Google Scholar 

  3. Vitellas KM, Bennett WF, Bova JG et al (1993) Idiopathic eosinophilic esophagitis. Radiology 186:789–793

    CAS  PubMed  Google Scholar 

  4. Landres RT, Kuster GGR, Strum WB (1978) Eosinophilic esophagitis in a patient with vigorous achalasia. Gastroenterlogy 74:1298–1301

    CAS  Google Scholar 

  5. Noel RJ, Putnam PE, Rothenberg ME (2004) Eosinophilic esophagitis (letter) N Engl J Med 35:940–941

    Google Scholar 

  6. Engel MA et al (2008) Eosinophile Ösophagitis: neue Standards in Diagnostik und Therapie chronischer Retrosternalschmerzen. Dtsch Med Wochenschr 133:966–971

    Article  CAS  PubMed  Google Scholar 

  7. Sgouros SN, Bergele C, Mantides A (2006) Eosinophilic esophagitis in adults: a systematic review. Eur J Gastroenterol Hepatol 18(2):211–217

    Article  PubMed  Google Scholar 

  8. Straumann A, Hruz P (2009) What’s new in the diagnosis and therapy of eosinophilic esophagitis? Curr Opin Gastroenterol 4(25):366–371

    Article  Google Scholar 

  9. Prasad GA, Talley NJ, Romero Y et al (2007) Prevalence and predictive factors of eosinophilic oesophagitis in patients presenting with dysphagia: a prospective study. Am J Gastroenterol 102:2627–2632

    Article  PubMed  Google Scholar 

  10. Moawad FJ et al (2009) Eosinophile gastritis. Dig Dis Sci 54:1818–1828

    Article  PubMed  Google Scholar 

  11. Straumann A (2009) Clinical evaluation of the adult who has eosinophilic esophagitis. Immunol Allergy Clin North Am 29:11–18

    Article  PubMed  Google Scholar 

  12. Ronkainen J, Talley NJ, Aro P et al (2007) Prevalence of oesophageal eosinophils and eosinophilic oesophagitis in adults: the population-based kalixanda study. Gut 56:615–620

    Article  PubMed  Google Scholar 

  13. Fox VL (2008) Eosinophilic esophagitis: Endoscopic findings. Gastrointest Endosc Clin North Am 18:45–57

    Article  Google Scholar 

  14. Muller S, Puhl S, Vieth M et al (2007) Analysis of symptoms and endoscopic features of Eosinophilic Esophagitis in 117 patients with histolological diagnoses of eosinophilic esophagitis. Endoscopy 39(4):339–344

    Article  CAS  PubMed  Google Scholar 

  15. Yan BM, Shaffer EA (2006) Eosinophilic esophagitis: a newly established cause of dysphagia. World J Gastroenterol 12(16):2328–2334

    PubMed  Google Scholar 

  16. Attwood SE, Lamb CA (2008) eosinophilic oesophagitis and other non-reflux inflammatory conditions of the oesophagus: Diagnostic imaging and management. Best Pract Res Clin Gastroenterol 22(4):639–660

    Article  PubMed  Google Scholar 

Download references

Interessenkonflikt

Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to G. Böhm M.D., FRCS Engl..

Rights and permissions

Reprints and permissions

About this article

Cite this article

Froeschen-Behrens, S., Kuth, N., Gassler, N. et al. Eosinophile Ösophagitis. Chirurg 81, 1026–1030 (2010). https://doi.org/10.1007/s00104-010-1923-5

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00104-010-1923-5

Schlüsselwörter

Keywords

Navigation