Skip to main content
Log in

Acute stent thrombosis during percutaneous coronary intervention

Treatment with tirofiban

Akute Stentthrombose während perkutaner Koronarintervention

Therapie mit Tirofiban

  • Case study
  • Published:
Herz Aims and scope Submit manuscript

Abstract

Although rarely reported, acute instent thrombosis can be life threatening, especially in cases where there are no ST segment changes. For this reason, careful history taking, follow-up, and prompt coronary angiography may be lifesaving. Herein, a case of acute stent thrombosis with no ST segment changes on electrocardiogram that was resolved with intracoronary tirofiban is presented.

Zusammenfassung

Über die akute Thrombose innerhalb eines Stents wird zwar nur selten berichtet, sie kann aber lebensbedrohlich sein, insbesondere in Fällen, in denen keine ST-Strecken-Veränderungen bestehen. Daher können sorgfältige Anamneseerhebung, Nachsorge und prompte Koronarangiographie lebensrettend sein. Hier wird ein Fall einer akuten Stentthrombose ohne ST-Strecken-Veränderungen im Elektrokardiogramm beschrieben, die mit intrakoronarer Tirofibanapplikation aufgelöst wurde.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

References

  1. Dangas G, Colombo A (1999) Platelet glycoprotein IIb/IIIa antagonists in percutaneous coronary revascularization. Am Heart J 138:S16–23

    Article  PubMed  CAS  Google Scholar 

  2. Koutouzis M, Albertsson P, Ioanes D et al (2010) Recurrent bare metal stent thrombosis: six years, single center experience. Int J Cardiol 144:234–235

    Article  PubMed  Google Scholar 

  3. Cutlip DE, Baim DS, Ho KK et al (2001) Stent thrombosis in the modern era: a pooled analysis of multicenter coronary stent clinical trials. Circulation 103:1967–1971

    PubMed  CAS  Google Scholar 

  4. Jeong MH, Owen WG, Staab ME et al (1996) Porcine model of stent thrombosis: platelets are the primary component of acute stent closure. Cathet Cardiovasc Diagn 38:38–43

    Article  PubMed  CAS  Google Scholar 

  5. Wenaweser P, Rey C, Eberli FR et al (2005) Stent thrombosis following bare-metal stent implantation: success of emergency percutaneous coronary intervention and predictors of adverse outcome. Eur Heart J 26:1180–1187

    Article  PubMed  Google Scholar 

  6. Siddiqui DS, Choi CJ, Tsimikas S, Mahmud E (2006) Successful utilization of a novel aspiration thrombectomy catheter (Pronto) for the treatment of patients with stent thrombosis. Catheter Cardiovasc Interv 67:894–899

    Article  PubMed  Google Scholar 

  7. Wijns W, Kolh P, Danchin N et al (2010) Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J 31:2501–2555

    Article  PubMed  Google Scholar 

  8. Silber S, Albertsson P, Aviles FF et al (2005) Guidelines for percutaneous coronary interventions. The Task Force for Percutaneous Coronary Interventions of the European Society of Cardiology. Eur Heart J 26:804–847

    Article  PubMed  Google Scholar 

  9. Wijns W, Kolh P, Danchin N et al (2010) Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J 31:2501–2555

    Article  PubMed  Google Scholar 

  10. Casserly IP, Hasdai D, Berger PB et al (1998) Usefulness of abciximab for treatment of early coronary artery stent thrombosis. Am J Cardiol 82:981–985

    Article  PubMed  CAS  Google Scholar 

  11. Winter JP, Juergens CP (2008) The role of tirofiban in the management of coronary artery disease. Cardiovasc Hematol Disord Drug Targets 8:138–146

    Article  PubMed  CAS  Google Scholar 

  12. Valgimigli M, Biondi-Zoccai G, Tebaldi M et al (2010) Tirofiban as adjunctive therapy for acute coronary syndromes and percutaneous coronary intervention: a meta-analysis of randomized trials. Eur Heart J 31:35–49

    Article  PubMed  CAS  Google Scholar 

  13. Kushner FG, Hand M, Smith SC Jr et al (2009) 2009 focused updates: ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction (updating the 2004 guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005 guideline and 2007 focused update) a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 54:2205–2241

    Article  PubMed  Google Scholar 

  14. Boersma E, Harrington RA, Moliterno DJ, White H, Simoons ML (2002) Platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes. Lancet 360:342–343

    Article  PubMed  Google Scholar 

  15. Wright RS, Anderson JL, Adams CD et al (2011) ACCF/AHA Focused Update of the Guidelines for the Management of Patients With Unstable Angina/ Non-ST-Elevation Myocardial Infarction (Updating the 2007 Guideline): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 123:2022–2060

    Article  PubMed  Google Scholar 

  16. Wu TG, Zhao Q, Huang WG et al (2008) Effect of intracoronary tirofiban in patients undergoing percutaneous coronary intervention for acute coronary syndrome. Circ J 72:1605–1609

    Article  PubMed  Google Scholar 

  17. Kirma C, Erkol A, Pala S et al (2011) Intracoronary bolus-only compared with intravenous bolus plus infusion of tirofiban application in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Catheter Cardiovasc Interv. doi: 10.1002/ccd.213109

Download references

Conflict of interest

This article was not funded by any institution. The corresponding author states that there are no conflicts of interest.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to U. Canpolat M.D..

Rights and permissions

Reprints and permissions

About this article

Cite this article

Canpolat, U., Sunman, H., Yorgun, H. et al. Acute stent thrombosis during percutaneous coronary intervention . Herz 37, 333–335 (2012). https://doi.org/10.1007/s00059-011-3526-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00059-011-3526-4

Keywords

Schlüsselwörter

Navigation