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Visual perception and memory systems: from cortex to medial temporal lobe

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Abstract

Visual perception and memory are the most important components of vision processing in the brain. It was thought that the perceptual aspect of a visual stimulus occurs in visual cortical areas and that this serves as the substrate for the formation of visual memory in a distinct part of the brain called the medial temporal lobe. However, current evidence indicates that there is no functional separation of areas. Entire visual cortical pathways and connecting medial temporal lobe are important for both perception and visual memory. Though some aspects of this view are debated, evidence from both sides will be explored here. In this review, we will discuss the anatomical and functional architecture of the entire system and the implications of these structures in visual perception and memory.

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Acknowledgments

Research in the Khan laboratory on visual memory is supported by grants from the Ministerio de Ciencia e Innovación (BFU2009-07641 and BFU2010-16500) and Junta de Andalucia (CTS 586/09-11).

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Authors and Affiliations

  1. Laboratory of Neurobiology, CIMES, Facultad de Medicina, University of Malaga, 29071, Malaga, Spain

    Zafar U. Khan & Elisa Martín-Montañez

  2. Department of Medicine, University of Malaga, Malaga, Spain

    Zafar U. Khan

  3. Department of Pharmacology, Faculty of Medicine, University of Malaga, Malaga, Spain

    Elisa Martín-Montañez

  4. CIBERNED, Institute of Health Carlos III, Madrid, Spain

    Zafar U. Khan

  5. Glickenhaus Laboratory of Neuropsychology, Department of Neuroscience, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, USA

    Mark G. Baxter

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  1. Zafar U. Khan
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  2. Elisa Martín-Montañez
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  3. Mark G. Baxter
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Correspondence to Zafar U. Khan.

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Khan, Z.U., Martín-Montañez, E. & Baxter, M.G. Visual perception and memory systems: from cortex to medial temporal lobe. Cell. Mol. Life Sci. 68, 1737–1754 (2011). https://doi.org/10.1007/s00018-011-0641-6

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  • DOI: https://doi.org/10.1007/s00018-011-0641-6

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