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Early hypertension and prolonged mineralocorticoid therapy discontinuation in a child with salt-wasting 21-hydroxylase deficiency

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References

  1. Stewart PM. Mineralocorticoid hypertension. Lancet 1999, 353: 1341–7.

    Article  CAS  PubMed  Google Scholar 

  2. Vehaskari VM. Heritable forms of hypertension. Pediatr Nephrol 2009, 24: 1929–37.

    Article  PubMed Central  PubMed  Google Scholar 

  3. White PC, Speiser PW. Congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Endocr Rev 2000, 21: 245–91.

    CAS  PubMed  Google Scholar 

  4. Nebesio TD, Eugster EA. Observation of hypertension in children with 21-hydroxylase deficiency. Endocrine 2006, 30: 279–82.

    Article  CAS  PubMed  Google Scholar 

  5. Roche EF, Charmandari E, Dattani MT, Hindmarsh PC. Blood pressure in children and adolescents with congenital adrenal hyperplasia (21-hydroxylase deficiency): a preliminary report. Clin Endocrinol 2003, 58: 589–96.

    Article  Google Scholar 

  6. Völkl TM, Simm D, Dötsch J, Rascher W, Dörr HG. Altered 24-hour blood pressure profiles in children and adolescents with classical congenital adrenal hyperplasia due to 21-hydroxylase deficiency. J Clin Endocrinol Metab 2006, 91: 4888–95.

    Article  PubMed  Google Scholar 

  7. Cornean RE, Hindmarsh PC, Brook CG. Obesity in 21-hydroxylase deficient patients. Arch Dis Child 1998, 78: 261–3.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  8. Wasniewska M, Di Pasquale G, Rulli I, et al. In Sicilian ethnic group non classical congenital adrenal hyperplasia is frequently associated with a very mild genotype. J Endocrinol Invest 2007, 30: 181–5.

    Article  CAS  PubMed  Google Scholar 

  9. Cacciari E, Milani S, Balsamo A, et al. Italian cross-section growth chart for height, eight and BMI (2 to 20 year). J Endocrinol Invest 2006, 29: 581–93.

    Article  CAS  PubMed  Google Scholar 

  10. Haffner SM, Kennedy E, Gonzalez C, Stern MP, Miettinen H. A prospective analysis of the HOMA model. The Mexico City Diabetes Study. Diabetes Care 1996, 19: 1138–41.

    CAS  Google Scholar 

  11. Falkner B, Gidding SS, Ramirez-Garnica G, Wiltrout SA, West D, Rappaport EB. The relationship of body mass index and blood pressure in primary care pediatric patients. J Pediatr 2006, 148: 195–200.

    Article  PubMed  Google Scholar 

  12. Joint LWPES/ESPE CAH Working Group. Consensus statement on 21-hydroxylase deficiency from the Lawson Wilkins Pediatric Endocrine Society and European Society for Pediatric Endocrinology. J Clin Endocrinol Metab 2002, 87: 4048–53.

    Article  Google Scholar 

  13. Arlt W, Allolio B. Adrenal insufficiency. Lancet 2003, 361: 1881–93.

    Article  CAS  PubMed  Google Scholar 

  14. Gomes LG, Huang N, Agrawal V, Mendonca BB, Bachega TA, Miller WL Extraadrenal 21-hydroxylation by CYP2C19 and CYP3A4: effect on 21-hydroxylase deficiency. J Clin Endocrinol Metab 2009, 94: 89–95.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  15. Stevens JC, Hines RN, Gu C, et al. Developmental expression of the major human hepatic CYP3A enzymes. J Pharmacol Exp Ther 2003, 307: 573–82.

    Article  CAS  PubMed  Google Scholar 

  16. Koukouritaki SB, Manro JR, Marsh SA, et al. Developmental expression of human hepatic CYP2C9 and CYP2C19. J Pharmacol Exp Ther 2004, 308: 965–74.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Pediatrics, University of Messina, Messina, Italy

    M. Wasniewska, M. Valenzise, T. Aversa, S. Mirabelli, F. De Luca, F. L. De Luca & F. Lombardo

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  1. M. Wasniewska
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  2. M. Valenzise
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  3. T. Aversa
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  4. S. Mirabelli
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  5. F. De Luca
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  6. F. L. De Luca
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  7. F. Lombardo
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Wasniewska, M., Valenzise, M., Aversa, T. et al. Early hypertension and prolonged mineralocorticoid therapy discontinuation in a child with salt-wasting 21-hydroxylase deficiency. J Endocrinol Invest 34, 159–161 (2011). https://doi.org/10.1007/BF03347048

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