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Iodine status and thyroid volumes of school age children from Northern Cyprus

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Abstract

In an epidemiological study carried out in eight different inland and coastal areas from northern part of Cyprus Island 625 School Age Children (SAC) aged 9 and 10 years, underwent thyroid ultrasonography for determination of thyroid volume (TV). Urinary iodine concentration (UIC) was measured from morning urine samples taken from all of the children. Mean TV was 3.2±1.0 ml, 3.3±0.8 ml and 3.8±1.1 ml, 3.7±1.1 ml for 9- and 10-year-old girls and boys respectively. None of the SAC had TV exceeding recommended upper limits for their age and gender. Median UIC of the whole group was 120 μg/l (11–900 μg/l) and only 12.6% of the SAC had UIC below 50 μg/l indicating adequate iodine intake. In this first epidemiological survey conducted in the northern part of the Cyprus Island, iodine status was found to be satisfactory and goiter does not pose a public health problem at the time of the study. Periodical surveys are required especially for the regions which have marginally adequate values and for a coastal region with a significantly higher median value of UIC compared to the others (ie 458 μg/l) (p<0.001).

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References

  1. Micronutrient Deficiency Information System. Global prevalence of iodine deficiency disorders. MDIS working paper N° 1 WHO- Nutrition Unit 1993: 1–80.

    Google Scholar 

  2. Koutras D.A. Europe and Middle East. In: Stanbury J.B., Hetzel B.S. (Eds), Endemic goiter and endemic cretinism. John Wiley, New York, 1980, p. 79.

    Google Scholar 

  3. Langer P. Eastern and Southeastern Europe. In: Stanbury J.B., Hetzel B.S. (Eds), Endemic goiter and endemic cretinism. John Wiley, New York, 1980, p. 141–168.

    Google Scholar 

  4. König M.P. Die Kongenitale Hypothyrose und der Endemische Kretinismus. Springer-Verlag, Berlin, 1968, p. 1.

    Book  Google Scholar 

  5. Delange F., Vigneri R., Trimarchi F., Fileti S., Pezzino V., Squatrito S. Etiological factors of endemic goiter in North-Eastern Sicily. J. Endocrinol. Invest. 1978, 2: 137–142.

    Google Scholar 

  6. Jaffiol C., Manderscheid J.C., Gatina J.H., Baldet L., Percheron C. Incidence of endemic goiter on Reunion Island. A search for etiological factors. Presse Med. 1991, 20: 2139–2243.

    CAS  PubMed  Google Scholar 

  7. De Oliveria A.L., Goncalves M.J., Sobrinho L.G. Endemic goitre in the Island of S.Miguel (the Azores). Acta Endocrinol. (Copen). 1986, 111: 200–203.

    Google Scholar 

  8. King H., Finch C., King L.F., Senator G., Tscharke E., Alpers N.P. Thyroid function in a formerly goitrous community on Karkar. P.N.G. Med. J. 1992, 35: 26–32.

    CAS  PubMed  Google Scholar 

  9. Delange F., Ermans A.M., Vis L.H., Stanbury J.B. Endemic Cretinism in Idjwi Island (Kivu Lake, republic of the Congo). J. Clin. Endocrinol. Metab. 1972, 34: 1059–1066.

    Article  CAS  PubMed  Google Scholar 

  10. Delange F. Iodine deficiency in Europe. Thyroid Intern. 1994, 3: 1–5.

    Google Scholar 

  11. Delange F. The disorders induced by iodine deficiency. Thyroid 1994, 4: 107–128.

    Article  CAS  PubMed  Google Scholar 

  12. Progress Against IDD 1998: The Annual ICCIDD Board Meeting. IDD Newsletter 14: 2 May 1998.

  13. Delange F., Benker G., Caron P., Eber O., Ott W., Peter D., Podoba J., Simescu M., Szybinzsky Z., Vertongen F., Vitti P., Wiersinga W., Zamzarzill V. Thyroid volume and urinary iodine in European school children. Standardization of the values for assement of iodine deficiency. Eur. J. Endocrin. 1997, 136: 180–187.

    Article  CAS  Google Scholar 

  14. Recommended normative values for thyroid volume in children aged 6–15 years. World Health Organisation (International Council for Control of Iodine Deficiency Disorders. WHO Bulletin OMS 1997, 75: 95–97.

  15. Vitti P., Martino E., Aghini-Lombardi F., Rago T., Antonangelli L., Maccherini, Nanni P, Loviselli A., Balestrieri A., Araneo G. Thyroid volume measurement by ultrasound in children as a tool for the assessment of mild iodine deficiency. J. Clin. Endocrinol. Metab. 1994, 79: 600–603.

    CAS  PubMed  Google Scholar 

  16. Brunn J., Blocjk U., Ruf J., Kunze Bos I., Kunza W.P., Scriba P.C. Volumetrie der Schildrüsenlappen mittels Real-time-sonographie. Deutsche Medizinische 1991 Wochenschriftt 1981, 106: 1338–1340.

    Article  CAS  Google Scholar 

  17. Sandell E.B., Kolthoff I.M. Micro determination of iodine by a catalytic method. Mikrochemica Akta 1937, 1: 9–12.

    Article  CAS  Google Scholar 

  18. Dunn J.T., Crutchfield E.H., Gutekunst R., Dunn A.D. Methods for Measuring Iodine in Urine. International Council For Control of Iodine Deficiency Disorders, 1993.

    Google Scholar 

  19. Hetzel B.S. The Story of Iodine Deficiency. Oxford University Press, Oxford, 1989, p. 1.

    Google Scholar 

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Erdoğan, G., Sav, H. & Erdoğan, M.F. Iodine status and thyroid volumes of school age children from Northern Cyprus. J Endocrinol Invest 23, 74–77 (2000). https://doi.org/10.1007/BF03343682

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