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Detecting and Treating Cancer with Nanotechnology

  • Cancer
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Abstract

Nanotechnology offers many opportunities for enhanced diagnostic and therapeutic medicine against cancer and other diseases. In this review, the special properties that result from the nanoscale size of quantum dots, metal colloids, superparamagnetic iron oxide, and carbon-based nanostructures are reviewed and interpreted against a background of the structural and electronic detail that gives rise to their nanotechnologic behavior. The detection and treatment of cancer is emphasized, with special attention paid to the biologic targeting of the disease. The future of nanotechnology in cancer research and clinical practice is projected to focus on ‘theranostic’ nanoparticles that are both diagnostic and therapeutic by design.

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Acknowledgments

The authors wish to thank the Robert A. Welch Foundation (grant no. C-0627 to Dr Wilson) and the Center for Biological the Environmental Nanotechnology (grant no. NSF EEC-0118007 to Drs Wilson and Hartman). Dr Hartman is a recipient of the Rice University Norman Hackerman Fellowship in Chemistry.

The authors have no conflicts of interest that are directly relevant to the content of this review.

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Authors and Affiliations

  1. Department of Chemistry, Richard E. Smalley Center for Nanoscale Science and Technology, and Center for Biological and Environmental Nanotechnology, Rice University, Houston, Texas, USA

    Keith B. Hartman &  Lon J. Wilson

  2. Department of Experimental Therapeutics, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA

    Michael G. Rosenblum

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  1. Keith B. Hartman
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  2. Lon J. Wilson
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  3. Michael G. Rosenblum
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Correspondence to Lon J. Wilson.

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Hartman, K.B., Wilson, L.J. & Rosenblum, M.G. Detecting and Treating Cancer with Nanotechnology. Mol Diag Ther 12, 1–14 (2008). https://doi.org/10.1007/BF03256264

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