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Spectroscopic studies of biologically active organotin(IV) derivatives of 2-[N-(2,4,6-tribromophenylamido]propanoic acid

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Abstract

Herein we describe the synthesis and characterization of compounds having the formulae R2SnL2 and R3SnL, where R = Me, n-Bu, Ph and n-Oct and L = 2-[N-(2,4,6-tribromophenylamido]propanoic acid. All the complexes have been characterized by various spectroscopic methods (IR and 1H, 13C, 119Sn NMR), elemental analysis, mass spectrometry and physical data. These compounds were also screened for their biological activity and found some encouraging results.

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References

  1. A.G. Davis, P.G. Smith, in: G. Wilkinson, F.G.A. Stone, E.W. Abel (Eds.), Comprehensive Organometallic Chemistry, Pergamon, Oxford, UK, 1982.

    Google Scholar 

  2. M. Pereyer, J.P. Quintard, A. Rahim, Tin in Organic Synthesis, Butterworth, London, 1987.

    Google Scholar 

  3. D. Martin, U. Russo, D. Stivanello, G. Tagliavini, Organometallics 15 (1996) 1645.

    Google Scholar 

  4. G.S. Drummond, A. Kappass, Proc. Natl. Acad. Sci. 78 (1981) 6466.

    CAS  Google Scholar 

  5. K.C. Molloy, T.G. Purcell, K. Quil, I.W. Nowell, J. Organomet. Chem. 267 (1984) 237.

    CAS  Google Scholar 

  6. K.C. Molloy, T.G. Purcell, E. Mahn, H. Schumann, J.J. Zuckerman, Organometallics 5 (1986) 85.

    CAS  Google Scholar 

  7. A. Ruzicka, L. Dostal, R. Jambor, V. Buchta, J. Brus, I. Cisarova, M. Holcapek, J. Holecek, Appl. Organomet. Chem. 16 (2002) 315.

    CAS  Google Scholar 

  8. K. Shahid, S. Ali, S. Shahzadi, A. Badshah, K.M. Khan, G.M. Maharvi, Synth. React. Inorg. Met.-Org. Chem. 33 (2003) 1221.

    CAS  Google Scholar 

  9. S. Shahzadi, K. Shahid, S. Ali, M. Mazhar, K.M. Khan, J. Iran. Chem. Soc. 2 (2005) 277.

    Article  CAS  Google Scholar 

  10. M. Gielen, A. El-Khaloufi, F. Kayrev, M. Biesemans, R. Willem, Appl. Organomet. Chem. 7 (1993) 201.

    CAS  Google Scholar 

  11. Q.L. Xie, Z.Q. Yang, Z.X. Zhang, D.K. Zhang, Appl. Organomet. Chem. 6 (1992) 193.

    CAS  Google Scholar 

  12. Q. Xie, Z. Yang, L. Jiang, Main Group Met. Chem. 19 (1996) 509.

    CAS  Google Scholar 

  13. Sadiq-ur-Rehman, S. Ali, A. Badshah, A. Malik, E. Ahmed, G.-X. Jin, E.R.T. Tiekink, Appl. Organomet. Chem. 18 (2004) 401.

    CAS  Google Scholar 

  14. Sadiq-ur-Rehman, K. Shahid, S. Ali, M. Mazhar, A. Badshah, G. Eng, X. Song, J. Ryczkowski, Heteroatom Chem. 16 (2005) 175.

    CAS  Google Scholar 

  15. A. Badshah, M. Danish, S. Ali, M. Mazhar, S. Mahmood, M.I. Chaudhry, Synth. React. Inorg. Met. Org. Chem. 24 (1994) 1155.

    CAS  Google Scholar 

  16. T.N. Metchell, J. Organomet. Chem. 59 (1973) 189.

    Google Scholar 

  17. B. Jousseaume, J.G. Duboudin, M. Petraud, J. Organomet. Chem. 238 (1982) 171.

    CAS  Google Scholar 

  18. T.P. Lockhart, W.F. Manders. Inorg. Chem. 25 (1986) 892.

    CAS  Google Scholar 

  19. T.P. Lockhart, W.F. Manders, E.M. Holts, J. Am. Chem. Soc. 108 (1986) 6611.

    CAS  Google Scholar 

  20. S. Ali, F. Ahmad, M. Mazhar, A. Munir, M.T. Masood, Synth. React. Inorg. Met. -Org. Chem. 32 (2002) 357.

    CAS  Google Scholar 

  21. B. Wrackmeyer, G. Kehr, J. Süß Chem. Ber. 126 (1993) 2221.

    CAS  Google Scholar 

  22. K. Shahid, S. Ali, S. Shahzadi, Z. Akhtar, Turk. J. Chem. 27 (2003) 209.

    CAS  Google Scholar 

  23. K. Shahid, S. Shahzadi, S. Ali, M. Mazhar, Bull. Korean Chem. Soc. 27 (2006) 44.

    CAS  Google Scholar 

  24. S. Ahmad, S. Ali, S. Shahzadi, F. Ahmed, K.M. Khan, Turk. J. Chem. 29 (2005) 299.

    CAS  Google Scholar 

  25. Sadiq-ur-Rehman, S. Ali, S. Shahzadi, A. Malik, E. Ahmad, Turk. J. Chem. 31 (2007) 371.

    CAS  Google Scholar 

  26. J.M. Barnes, H.B. Stoner, Brit. J. Ind. Med. 15 (1958) 15.

    CAS  Google Scholar 

  27. H. Blank, G. Rewbell, Arch. Derm. 92 (1965) 319.

    Google Scholar 

  28. A. Rahman, M.I. Choudhry, W.J. Thomsen, Bioassay Techniques for Drug Development, Harward Academic Press, Amsterdam, 2001.

    Book  Google Scholar 

  29. S.S. Shaukat, N.A. Khan, F. Ahmed, Pak. J. Bot. 12 (1980) 97.

    CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Chemistry, Quaid-i-Azam University, Islamabad, 45320, Pakistan

    K. Shahid & S. Ali

  2. Department of Chemistry, GC University, Faisalabad, Pakistan

    S. Shahzadi

Authors
  1. K. Shahid
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  2. S. Shahzadi
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  3. S. Ali
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Correspondence to S. Ali.

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Shahid, K., Shahzadi, S. & Ali, S. Spectroscopic studies of biologically active organotin(IV) derivatives of 2-[N-(2,4,6-tribromophenylamido]propanoic acid. JICS 5, 579–587 (2008). https://doi.org/10.1007/BF03246137

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  • DOI: https://doi.org/10.1007/BF03246137

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