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MPEG-b-poly(amino urethane) amphiphilic block copolymers and their pH-Dependent micellization behavior

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Conclusions

The MPEG-PAU block coplymers were successfully synthesized and their chemical structures were well characterized by1H,13C NMR and FT-IR spectroscopies. The aqueous solution properties of the copolymers were evaluated by acid-base titration, fluorescence spectroscopy and dynamic light scattering. The block copolymers exhibited a pHdependent micellization-demicellization transition in aqueous solution. The fluorescence spectroscopy and DLS measurements indicate that the micellization-demicellization transition occurs at pH 6.0–6.6. The amphiphilic block copolymers are expected to find applications in biomedical field.

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Authors and Affiliations

  1. Polymer Technology Institute, Sungkyunkwan University, 440-746, Gyeonggi, Korea

    Kasala Dayananda, Chaoliang He & Ying Qian Hu

  2. Department of Polymer Science and Engineering, Sungkyunkwan University, 440-746, Gyeonggi, Korea

    Min Sang Kim & Doo Sung Lee

Authors
  1. Kasala Dayananda
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  2. Chaoliang He
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  3. Ying Qian Hu
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  4. Min Sang Kim
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  5. Doo Sung Lee
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Correspondence to Doo Sung Lee.

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Dayananda, K., He, C., Hu, Y.Q. et al. MPEG-b-poly(amino urethane) amphiphilic block copolymers and their pH-Dependent micellization behavior. Macromol. Res. 17, 58–61 (2009). https://doi.org/10.1007/BF03218602

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  • DOI: https://doi.org/10.1007/BF03218602

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