Abstract
Background
The aim of this paper was to evaluate patient and kidney graft survival rates in renal transplant recipients and compare the outcomes between the different patient age groups.
Methods
A retrospective review of all adult renal transplants performed at Beaumont Hospital between the years 1986–2001 was carried out. Patients were defined as ‘elderly’ if they were 65 years of age or older and ‘younger’ if less than 65 years at the time of transplantation. Patient and transplant graft survival rates were analysed for each age group.
Results
Data were analysed on 1462 ‘younger’ patients and 105 ‘elderly’ renal transplant recipients. Estimated patient survival at 1, 5 and 10 years were 96%, 87% and 74% in the younger patient group compared to 85%, 59% and 33% in the elderly group. The adjusted graft survival rates (adjusted for death due to other causes and with a functioning graft in situ) for the younger group were 89%, 77% and 64% at one, five and ten years respectively, while for the elderly group, adjusted one, five and ten year survival rates were 89%, 83% and 70% respectively
Conclusions
Although the elderly have a shorter life expectancy than the younger population they do benefit from renal transplantation similar to the younger recipients.
Similar content being viewed by others
References
Bureau of the Census. Current Population Reports, 2002. www.cso.ie/principlestats/pristat7.html — life expectancy report.
Braun, WE. Allocation of cadaveric kidneys, new pressures, new solutions.Am J Kidney Dis. 1994; 24:526–530.
Segoloni G, Messina M, Tognarelli G et al. Survival probabilities for renal transplant recipients and dialytic patients — a single centre prospective study.Transplant Proc. 1998; 30:1739–41
Becker BN, Ismail N, Becker YT, MacDonnell RC, Helderman JH. Renal transplantation in the older end stage renal disease patient.Am J Kidney Dis. 1996; 16: 353–362.
Vivas C, Hickey D, Jordan M et al. Renal Transplantation in Patients 65 years or Older. J Urology 1992; 147: 990–993.
United States Renal Data System. USRDS 2001 annual data report. Bethesda, MD. National Institute of Diabetes and Digestive and Kidney Diseases, June 2001.
Schaubel D, Desmeules M, Mao Y, Jeffery J, Fenton S. Survival experience among elderly end-stage renal disease patients.Transplantation 1995; 60(12): 1389–1394.
Bonal J, Clèries M, Vela E and the Renal Registry Committee. Transplantation versus haemodialysis in elderly patients.Nephrol Dial Transplant 1997; 12:261–264.
Greenstein S, Siegal B. Compliance and noncompliance in patients with a functioning renal transplant; a multicentre study.Transplantation 1999; 66: 1718–1726.
Cecka JM.The UNOS Scientific Renal Transplant Registry 2000.Clin. Transpl. 2000: 1–18.
Briggs JD. Causes of Geath after renal transplantation.Nephrol Dial Transplant 2001; 16: 1545–1549.
Wolfe RA, Ashby VB, Milford EL et al. Comparison of Mortality in All Patients on Dialysis, Patients on Dialysis Awaiting Transplantation, and Recipients of a First Cadaveric Transplant.NEJM 1999; 341: 1725–1730.
Kreis HA, Ponticeili C. Causes of late renal allograft loss: chronic allograft dysfunction, death and other factors.Transplantation 2001 Jun 15; 71(11 Supp) SS5–9.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Giblin, L., Hollander, M., Little, D. et al. Renal transplantation in the elderly — the Irish experience. Ir J Med Sci 174, 9–13 (2005). https://doi.org/10.1007/BF03169122
Issue Date:
DOI: https://doi.org/10.1007/BF03169122