Skip to main content
Log in

Studies on hemorrheology in dogs with cirrhotic portal hypertension

  • Published:
Journal of Tongji Medical University Aims and scope Submit manuscript

Summary

Eight dogs with cirrhotic portal hypertension were investigated for hemorrheology and hepatic hemodynamics. The whole-blood viscosity decreased in dogs with liver cirrhosis. The decrease in hematocrit may be responsible for low blood viscosity in cirrhosis. It was also found that the increase in portal venous resistance in cirrhosis was related to the anatomical changes of portal venous bed, but not to blood viscosity. Moreover, our experimental results indicated that raising blood viscosity might be one of the important measures for the treatment of esophageal variceal hemorrhage and for the prevention of rebleeding.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Mayer GA. Relation of the viscosity of plasma and whole blood. Am J Clin Pathol 1965;45:273–6.

    Google Scholar 

  2. Rand PW, et al. Effects of plasma viscosity and aggregation on whole-blood viscosity. Am J Physiol 1970;218:681–8.

    PubMed  CAS  Google Scholar 

  3. Leonhardt H, et al. Plasmaviskosität und portale Hypertension bei Lebercir-rhosekranken. Klin Wschr 1973;51:1043–9.

    Article  Google Scholar 

  4. Leonhardt H, et al. Vollblut- und Plasmaviskosität bei der Leberzirrhose mit und ohne Umgehungskreislauf. Wiener Klin Wschr 1974;86(11):21–2.

    CAS  Google Scholar 

  5. Polio J, et al. Hemodynamic factors involved in the development and rupture of esophageal varices: A pathophysiologic approach to treatment. Seminars in Liver Disease 1986;6(4):318–31.

    Article  PubMed  CAS  Google Scholar 

  6. Folkow B, et al. Circulation. London, Oxford University Press, a971;pp 14–9.

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Zi-li, D., Shao-bai, L. Studies on hemorrheology in dogs with cirrhotic portal hypertension. Journal of Tongji Medical University 10, 146–149 (1990). https://doi.org/10.1007/BF02986452

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02986452

Key words

Navigation