Skip to main content
Log in

Normal bone density in Irish women: is American normative data suitable for use in Ireland?

  • Published:
Irish Journal of Medical Science Aims and scope Submit manuscript

Summary

The object of the study was to determine whether or not U.S. normal data for female Vertebral Bone Mineral Density is suitable for use in an Irish population. One hundred and fifty-six healthy Caucasian women of permanent Irish domicile had bone densitometry performed using single energy quantative computed tomography of L2, L3 and L4 vertebrae. We found that comparison of our results to normal American data shows a slight and progressive increase in bone mineral content of postmenopausal American women with age relative to the Irish population. This difference is small and not sufficient to justify development of separate normal values for Irish women. We conclude that this discrepancy may be due to a combination of environmental and racial factors or to the more rigorous exclusion criteria applied in our study.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Cann, E., Genant, H. Precise measurement of vertebral mineral content using computer tomography. Journal of Computer Assisted Tomography 1980: 4, 493–500.

    Article  PubMed  CAS  Google Scholar 

  2. Cummings, S. R., Browner, W. S., Grady, D., Ettinger, B. Should prescription of postmenopausal therapy be based on the results of bone densitometry? Annals of Internai Medicine 1990: Editorial 113, 565–567.

    CAS  Google Scholar 

  3. Genant, H. K., Cann, E., Pozzi-Mucelli, R. S., Kanter, A. S. Vertebral mineral determination by Quantative C.T.: Clinical feasability and normative data. Journal of Computer Assisted Tomography 1983: 7, 554–555.

    Article  Google Scholar 

  4. Genant, H. K., Cann, E., Ettinger, Gordan, G. S. Quantative computed tomography of vertebral spongiosa: A sensitive method for detecting early bone loss after oophrectomy. Annals of Internal Medicine 1982: 97, 699–705.

    PubMed  CAS  Google Scholar 

  5. Genant, H., Blocke, J. E., Steiger, P., Glueer, Ettinger, Appropriate use of bone densitometry. Radiology 1989: 170, 817–822.

    PubMed  CAS  Google Scholar 

  6. Melton, L. J. 3rd, Eddy, D. M., Johnston, Jr. Screening for osteoporosis. Annals of Internal Medicine 1990: 112, 516–528.

    PubMed  Google Scholar 

  7. Hall, M. L., Heavens, J., Cullum, I. D., Eu, P. J. The range of bone density in normal British women. The British Journal of Radiology 1990: 63, 266–269.

    PubMed  CAS  Google Scholar 

  8. Compson, J. E., Evans, W. D., Crawley, E. O., Evans, C. Bone mineral content in normal U.K. subjects. The British Journal of Radiology 1988: 61, 631–636.

    Google Scholar 

  9. Kalender, W. A., Klotz, E., Suess, C. Vertebral bone mineral analysis: An integrated approach with C.T. Radiology 1987: 164, 419–423.

    PubMed  CAS  Google Scholar 

  10. Steiger, P., Block, J. E., Steiger, S., Heuck, A. F., Friedlander, A., Ettinger, B., Harris, S. T., Glueer, Genant, H. K. Spinal bone mineral density measured with quantative Effect of region of interest, vertebral level and technique. Radiology 1990: 175, 537–543.

    PubMed  CAS  Google Scholar 

  11. Genant, H. Steiger, P., Glueer, New developments in bone densitometry. Postgraduate Medicine 1989: April spec p. 18–22, 33–43.

  12. Banks, L. M., Stevenson, J. Modified method of spinal computed tomography for trabecular bone mineral measurements. Journal of Computer Assisted Tomography 1986: 10, 463–467.

    Article  PubMed  CAS  Google Scholar 

  13. Riggs, R. L., Wanner, H. W., Dunn, W. L., Mazess, R., Offord, K. P., Melton, L. J. 3rd. Differential changes in bone mineral density of the appendicular and axial skeleton with aging: Relationship to spinal osteoporosis. Journal of Clinical Investigation 1981: 67, 328–335.

    Article  PubMed  CAS  Google Scholar 

  14. Pacifici, R., Susman, N., Carr, P. L., Birge, S. J., Avioli, L. V. Single and dual energy tomographic analysis of spinal trabecular bone: A comparative study in normal and osteoporotic women. Journal of Clinical Endocrinology and Metabolism 1987: 64, 209–214.

    Article  PubMed  CAS  Google Scholar 

  15. Pacifici, R., Rupich, R., Griffin, M., Chines, A., Susman, N., Avioli, L. V. Dual energy radiography versus quantative computed tomography for the diagnosis of osteoporosis. Journal of Clinical Endocrinology and Metabolism 1990: 70, 705–710.

    PubMed  CAS  Google Scholar 

  16. Reinbold, W. D., Genant, H., Reiser, U. J., Harris, S. T., Ettinger, B. Bone mineral content in early-postmenopausal and postmenopausal osteoporotic women: Comparison of measurement methods. Radiology 1986: 160, 469–478.

    PubMed  CAS  Google Scholar 

  17. Buchanan, J. R., Myers, C, Greer, R. B. 3rd, Lloyd, T., Varano, L. A. Assessment of the risk of vertebral fracture in menopausal women. Journal of Bone and Joint Surgery 1987: 69, 212–218.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Harbison, J., Daly, L., Murphy, B. et al. Normal bone density in Irish women: is American normative data suitable for use in Ireland?. I.J.M.S. 161, 66–69 (1992). https://doi.org/10.1007/BF02983715

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02983715

Keywords

Navigation