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Mammary ductoscopy for diagnosis and treatment of intraductal lesions of the breast

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Abstract

Background

Mammary ductoscopy (mammoscopy) is an ideal diagnostic method for intraductal lesions. The usefulness of mammoscopy for intraductal lesions was evaluated.

Methods

Mammoscopy was performed in 315 cases with nipple discharge. The mammoscopic findings of 46 breast cancer cases (47 lesions) and 109 intraductal papilloma cases (119 lesions) were compared with pathological findings.

Results

Carcinoma was recognized by mammoscopy in 38 of 47 lesions (80.9%). Intraductal masses were detected by mammoscopy in 115 of 119 intraductal papilloma lesions. The shape of the mass was classified as hemispheric, papillary, or flat protrusion. The hemispheric and papillary shapes were most common in cases of intraductal papilloma and the flat protrusion type was most common in cases of carcinoma. The amount of material collected by intraductal biopsy under mammoscopic observation was smaller in carcinoma than in intraductal papilloma because the carcinoma lesions were usually located in peripheral ductlobular units and had weak tissue cohesion compared with that of intraductal papilloma. Of 133 intraductal biopsies performed for 69 intraductal papillomas, 17 biopsies yielded material insufficient for diagnosis in. The effectiveness of treatment by intraductal biopsy was recognized in 38 of 46 intraductal papillomas in which clinical follow-up continued for more than two years (82.6%). The therapeutic results of biopsy were poor in cases of multiple intraductal masses in multiple duct-lobular units.

Conclusions

Mammoscopy contributes not only the diagnosis in cases of nipple discharge, but is also of benefit in the treatment of intraductal papilloma.

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Authors and Affiliations

  1. Department of Breast Cancer Research, Tokyo Metropolitan Cancer Detection Center, Japan

    Tadaharu Matsunaga, Daisuke Ohta, Takeharu Misaka & Katsumasa Hosokawa

  2. Department of Pathology, Kyorin University School of Health Science, Japan

    Masahiko Fujii

  3. Third Department of Surgery, Tokyo Medical University, Japan

    Shun Nakayama, Hiroshi Kaise, Mikihiro Kusama & Yasuhisa Koyanagi

Authors
  1. Tadaharu Matsunaga
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  2. Daisuke Ohta
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  3. Takeharu Misaka
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  4. Katsumasa Hosokawa
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  5. Masahiko Fujii
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  6. Shun Nakayama
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  7. Hiroshi Kaise
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  8. Mikihiro Kusama
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  9. Yasuhisa Koyanagi
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Corresponding author

Correspondence to Tadaharu Matsunaga.

Additional information

Reprint requests to Tadaharu Matsunaga, Department of Breast Cancer Research, Tokyo Metropolitan Cancer Detection Center, 2-5 Kanda Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan.

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Matsunaga, T., Ohta, D., Misaka, T. et al. Mammary ductoscopy for diagnosis and treatment of intraductal lesions of the breast. Breast Cancer 8, 213–221 (2001). https://doi.org/10.1007/BF02967511

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  • DOI: https://doi.org/10.1007/BF02967511

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