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Staging of palpable tl-2 invasive breast cancer with helical ct

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Abstract

Background

The purpose of this study was to evaluate the accuracy of contrast-enhanced high resolution helical computed tomography (CT) for assessing locoregional staging of palpable Tl-2 invasive breast cancer. Methods: Helical CT studies of 156 lesions from 156 patients with invasive breast cancer before breast-conserving surgery were examined. A lesion was defined as positive if focal enhancement was detected by CT within 100 seconds after contrast material administration. After resection, tumors were histopathologically mapped and comparison made with the extent of contrast enhancement.

Results

Helical CT enabled detection of all 156 index tumors. CT enabled detection of 28 of 43 multifocal lesions (65%) and five of five multicentric lesions (100%). In 24 of 33 lesions (73%), CT revealed additional cancers not seen on mammography. The extent of tumor significantly correlated with CT measurements (r=0.76,p<0.0001).

Conclusion

Helical CT of the breast is an accurate preoperative imaging modality for assessing the locoregional staging of Tl-2 invasive breast cancer.

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Abbreviations

CT:

Computed tomography

MR:

Magnetic resonance

HU:

Hounsfield units

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Authors and Affiliations

  1. The Department of Radiology, Niigata Cancer Center Hospital, Japan

    Takayoshi Uematsu, Makoto Shiina, Shinichi Kobayashi & Katsuhide Shimizu

  2. The Department of Surgery, Niigata Cancer Center Hospital, Japan

    Muneaki Sano & Haruhiko Makino

  3. Department of Pathology, Niigata Cancer Center Hospital, Japan

    Keiichi Homma

Authors
  1. Takayoshi Uematsu
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  2. Muneaki Sano
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  3. Keiichi Homma
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  4. Haruhiko Makino
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  5. Makoto Shiina
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  6. Shinichi Kobayashi
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  7. Katsuhide Shimizu
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Uematsu, T., Sano, M., Homma, K. et al. Staging of palpable tl-2 invasive breast cancer with helical ct. Breast Cancer 8, 125–130 (2001). https://doi.org/10.1007/BF02967491

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  • DOI: https://doi.org/10.1007/BF02967491

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