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Clostridium septicum myonecrosis presenting as a parapharyngeal abscess in a patient with aplastic Anemia

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Summary

The first reported case ofClostridium septicum myonecrosis in an adult with aplastic anemia is described. The patient presented with sepsis, a parapharyngeal abscess that necessitated emergent intubation, and severe intravascular hemolysis attributed to clostridial α-toxin production. Despite prompt recognition and treatment, the patient died of his infection.C. septicum myonecrosis should be considered in any immunocompromised patient with sepsis, especially when accompanied by evidence of multiple sites of tissue infection.

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Authors and Affiliations

  1. Div. of Infectious Diseases, Duke University Medical Center, P. O. Box 3824, 27710, Durham, NC, USA

    V. G. Fowler M. D.

  2. Div. of Infectious Diseases, Duke University Medical Center, P. O. Box 3306, 27710, Durham, NC, USA

    C. D. Hamilton M. D.

  3. Infectious Diseases Section Brody 3E-117, East Carolina School of Medicine, 27858, Greenville, NC, USA

    C. A. Ohl M. D.

Authors
  1. V. G. Fowler M. D.
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  2. C. D. Hamilton M. D.
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  3. C. A. Ohl M. D.
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Fowler, V.G., Hamilton, C.D. & Ohl, C.A. Clostridium septicum myonecrosis presenting as a parapharyngeal abscess in a patient with aplastic Anemia. Infection 26, 309–310 (1998). https://doi.org/10.1007/BF02962255

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  • DOI: https://doi.org/10.1007/BF02962255

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