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High level of resistance to metronidazole and clarithromycin inHelicobacter pylori isolated from pediatric patients in Poland (1997–2001)

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Abstract

Resistance to metronidazole (Met), clarithromycin (Cla) and amoxycillin (Amo) was examined usingH. pylori isolates from child patients before and after treatment in the period 1997–2001. The rate of Met and Cla resistance before treatment was 35.2 and 8.6 %, respectively. Six weeks after treatment 48.4 % of the isolated strains were resistant to Met and 17.6 % to Cla. The highest rate of resistance to both antibiotics was determined in 2001 (before treatment, 46 and 15 %, respectively, and after treatment, 57.8 and 26.3 %, respectively). All the strains were susceptible to Amo. Strains resistant to Met were detected more frequently in girls than in boys.

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Abbreviations

Amo:

amoxycillin

Cla:

clarithromycin

Met:

metronidazole

Ome:

omeprazole

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Authors and Affiliations

  1. Department of Microbiology, University of Medicine, 50-368, Wroclaw, Poland

    G. Gościniak, A. Przondo-Mordarska & J. Grabińska

  2. Clinic of Pediatrics, Gastroenterology and Nutrition, University of Medicine, 50-368, Wroclaw, Poland

    B. Iwańczak & F. Iwańczak

Authors
  1. G. Gościniak
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  2. B. Iwańczak
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  3. A. Przondo-Mordarska
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  4. J. Grabińska
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  5. F. Iwańczak
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Gościniak, G., Iwańczak, B., Przondo-Mordarska, A. et al. High level of resistance to metronidazole and clarithromycin inHelicobacter pylori isolated from pediatric patients in Poland (1997–2001). Folia Microbiol 49, 133–136 (2004). https://doi.org/10.1007/BF02931386

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  • DOI: https://doi.org/10.1007/BF02931386

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