Summary
Antibodies against human prealbumin (HPA) give a strong immunoperoxidase staining of the A (glucagon) pancreatic cells and of glucagon-, insulin- and gastrin-producing pancreatic tumours. The majority of intestinal and bronchial carcinoids are also reactive.
The staining may be related to presence in the C-terminal sequence of HPA of determinants in common with polypeptide (pro-) hormones.
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Bussolati, G., Papotti, M. & Sapino, A. Binding of antibodies against human prealbumin to intestinal and bronchial carcinoids and to pancreatic endocrine tumours. Virchows Archiv B Cell Pathol 45, 15–22 (1984). https://doi.org/10.1007/BF02889848
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DOI: https://doi.org/10.1007/BF02889848