Abstract
Vitamin A status was measured in 50 pre-school children with acute and persistent diarrhoea. It was measured by (a) Fluorometric micromethod and (b) Conjunctival impression cytology (CIC). The results were compared with 25 normal children. Vitamin A status was lower in children with persistent diarrhoea whereas the results were comparable between the children with acute diarrhoea and control subjects.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Sommer, A. (1992) Bellagio brief on vitamin A deficiency. Indian Pediatr. 19, 1025–1027.
Sachdeva, H.P.S. and Puri, R.K. (1988) Vitamin A deficiency and diarrhoea. Indian Pediatr. 25, 911–913.
Sommer, A., Joanne, K. and Tarwotjo I. (1984) Increased risk of respiratory disease and diarrhoea with pre-existing mild vitamin A deficiency. Am. J. Clin. Nutr. 41, 1090–1095.
Milton, R.L., Reddy, V. and Naidu, A.N. (1987) Mild vitamin A deficiency and childhood morbidity —An Indian Experience. Am. J. Clin. Nutr. 46 827–829.
Vijayraghvan, K and Radhaiah, G. (1990) Effect of massive dose of vitamin A on morbidity and mortality in Indian children. Lancet 336, 1342–1345.
Natadisastra, G., Wittpenn, J.R., West, K.P., Muhilal. and Sommer, A. (1987) Impression cytology for detection of vitamin A deficiency. Arch. Ophthalmol. 105, 1224–1228.
Reddy, V., Rao, V., Arunjyoti and Reddy, M. (1989) Conjunctival impression cytology for assessment of vitamin A status. Am. J. Clin. Nutr. 50, 814–817.
Gadmoski, A.M., Kjolhede, C.L., Wittpenn, J.R., Bulux, J. and Rosas, A.R. (1989) Conjunctival impression cytology (CIC) to detect sub clinical vitamin A deficiency: comparison of CIC with biochemical assessment. Am. J. Clin. Nutr. 49, 495–500.
Mahalnabis, D., Wahed, M.A., Islam, M.et al. (1995) Conjunctival impression Cytology fails to detect sub clinical vitamin A deficiency in young children. J. Nutr. 125, 1869–1874.
Egbert, P., Lauber, S. and Maurice, D.M. (1977) A simple conjunctival biopsy. Am. J. Ophthalmol. 84, 798–801.
Driskell, W.J., Hewett, S. and Basher, M.M. (1986) Evaluation of a direct fluorometric method for the determination of serum retinol. Clin. Chem. 32, 867–869.
Scheffer, C.G. and Tseng. (1985) Impression cytology and squamous metaplasia. Ophthalmology 92, 728–733.
Shultz, E.K.: Selection and interpretation of laboratory procedures. In Tietz Text book of Clinical Chemistry, (edited by CA Burtis and AR Ashwood). 3rd ed, WB Saunders, Philadelphia, 1999 pp 310–319.
WHO Tech Report series (1982) Control of vitamin A deficiency and xerophthalmia. No. 672.
Indirabai, K., Bhatt, V. and Vaidyanathan, K. (1986) Epidemiological survey for prevalence of xerophthalmia. Indian Pediatr. 23, 135–139.
Natadisastra, G., Wittpenn, J.R., West, K.P., Muhilal and Sommer, A. (1988) Impression cytology: A practical index of vitamin A status. Am. J. Clin. Nutr. 48, 695–701
Moneseme, O.A., Luzeau, R., Wittpenn, J.R., Hanek, A. and Sommer, A. (1988) Impression cytology detects sub clinical vitamin A deficiency. Am. J. Clin. Nutr. 47, 875–878.
Faechem, R.G. (1987) Vitamin A deficiency and diarrhoea: A review of interrelationships and their implications for the control of xerophthalmia and diarrhoea. Trop. Disease Bulletin 84, 3 R1-R16.
Agarwal, D.K., Singh, S.V., Gupta, V. and Agarwal K.N. (1996) Vitamin A status in early childhood diarrhoea, respiratory infection and in maternal and cord blood. J. Trop. Pediatr. 42, 12–14.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Abrol, P., Mehta, U. & Lal, H. Vitamin a status in children with diarrhoea. Indian J Clin Biochem 17, 64–68 (2002). https://doi.org/10.1007/BF02867944
Issue Date:
DOI: https://doi.org/10.1007/BF02867944