Summary
The amount of T, B, Tγ as well as Tμ cells and the activity of antibody-dependent cellular cytotoxicity (ADCC) in the peripheral blood were studied in 40 cases of acute non-lymphocytic leukemia. The results demonstrated that the T cells decreased and the Tγ cells increased significantly in the acute stage, and both of them were of normal value again in complete remission; while the B cells and Tμ cells decreased in number and the ADCC activity also decreased before and after treatment as compared with the condition in normal individuals. The possible mechanism of these variations is discussed.
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References
Mendes NF, et al. Combined detection of human T and B lymphocytes by rosette formation with sheep erythrocytes and zymosan-C3 complexes. J Immunol 1974:113:531–6.
Moretta L, et al. Expression of a receptor for IgM by human T cells in vitro. Eur J Immunol 1975; 5:565
1976; 17: 506–14.
Pawel A. T-lymphocytes subpopulation in peripheral blood and tissue of cancer patients. Cancer Res 1980; 40:4648.
Kay NE, et al. T-cell subpopulation in chronic lymphocytic leukemia. Blood 1979; 54: 540.
Foon KA. et al. Leukemia of T-helper lymphocytes: Clinical and functional features. Leuk Res 1981;5:1–10.
Gupta RK, et al. Subpopulations of human T lymphocytes.VI: Cellular basis of concanvalin A-induced T cell-mediated — suppression of immunogloblin production by B lymphocytes from normal humans. Cell Immunol 1979; 44:242.
Werner J. Bedeutung von Fc-IgG und Fc-IgM Rezeptoren auf menschlichen T-Lymphozyten. Klin Wochenschr 1981; 59:99–109.
Jakobisiak M, et al. Decreased ADCC in various types of leukemia in man. Scand Haematol 1981; 27:181–5.
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Mu-xiang, Z., Ling-yi, W., Guan-xin, S. et al. Studies on the lymphocytic subpopulations in acute non-lymphocytic leukemia. Acta Academiae Medicinae Wuhan 4, 216–219 (1984). https://doi.org/10.1007/BF02857167
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DOI: https://doi.org/10.1007/BF02857167